Results 111 to 120 of about 823,203 (277)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Patterned Fluidity of Chinese Ethnic Identity: Networks, Time, and Place

open access: yesSAGE Open, 2017
This study tests the salience/prominence of Chinese ethnic identity by applying identity theory, social identity theory, and social network analysis.
Cynthia Baiqing Zhang
doaj   +1 more source

Ethnosizing Immigrants [PDF]

open access: yes
The paper provides a new measure of the ethnic identity of immigrants and explores its evolution in the host country. The ethnosizer, a measure of the intensity of a person's ethnic identity, is constructed from information on the following elements ...
Amelie Constant   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Intermarriage and Ethnicity: Punjabi Mexican Americans, Mexican Japanese, and Filipino Americans [PDF]

open access: yes, 1993
The problem is intermarriage, specifically intermarriages patterned by gender (all the men are from one ethnic background and almost all of the women from another) which produce significant biethnic communities.
Leonard, Karen B.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Alcohol Use In Mexican-Americans By Nativity: The Role Of Ethnic Identity, Acculturation, And Acculturative Stress [PDF]

open access: yes, 2013
The present study examined alcohol use disorder symptoms among Mexican-Americans. Participants consisted of a community-based sample of 237 Mexican-American adults living in the Midwest United States. The role of nativity status and cultural variables in
Vallejo, Leticia G.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The Pathology of Ethnic Issues in Iran [PDF]

open access: yesTaḥqīqāt-i Farhangī-i Īrān, 2010
This study is performed to use quantitative and survey method among Arabs people of Ahwaz. In this research ethnic identity of Arabs is taken as one of the social problems and its consequences in three dimensions are studied: 1) Reduction of national ...
Abdollreza Navvah   +2 more
doaj  

Tongues United: Polyphonic Identities and the Hispanic Family [PDF]

open access: yes, 2006
In this paper I will use the Bakhtinian notion of polyphony,1 of a choral dialogue of multiple and heterogeneous voices, to elaborate a pluralistic account of cultural identity in general and of Hispanic identity in particular.
Medina, José
core   +1 more source

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