Results 91 to 100 of about 756,284 (309)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

NCAPD2 is a favorable predictor of prognostic and immunotherapeutic biomarker for multiple cancer types including lung cancer

Genes and Environment
Background Non-SMC condensin I complex subunit D2 (NCAPD2) belongs to the chromosomal structural maintenance family. While the different contribution of NCAPD2 to chromosome in mitosis have been thoroughly investigated, much less is known about the ...
Linyuan Feng, Yang Yang, Zhenhua Lin, Minghua Cui, Aihua Jin, Aili Cui   +5 more
doaj   +1 more source

Spatial Variation in Responses of Plant Spring Phenology to Climate Warming in Grasslands of Inner Mongolia: Drivers and Application

Plants
Plant spring phenology in grasslands distributed in the Northern Hemisphere is highly responsive to climate warming. The growth of plants is intricately influenced by not only air temperature but also precipitation and soil factors, both of which exhibit
Guang Lu, Mengchao Fang, Shuping Zhang
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Iron Ion‐Mediated Nitrogen‐Doped Carbon Dot Fluorescence Sensing for Accurate Detection of Fluoroquinolone in Food

Food Frontiers
Safety incidents involving the presence of fluoroquinolones (FQs) residues in animal‐derived food are frequently reported, posing a significant threat to human health. Here, we constructed a fluorescence sensing method using iron ions as a bridge for the
Jinyan Luo, Yulong Han, Zikang Hu, Guanghua Lei, Huanhuan Lu, Hengye Chen, Li Yang, Xinming Lv, Wanjun Long, Haiyan Fu   +9 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Test Scores, Subjective Assessment and Stereotyping of Ethnic Minorities [PDF]

We assess whether ethnic minority pupils are subject to low teacher expectations. We exploit the English testing system of “quasi-blind” externally marked tests and “non-blind” internal assessment to compare differences in these assessment methods ...
Ellen Greaves, Simon Burgess
core  

Relative group size and minority school success: the role of intergroup friendship and discrimination experiences [PDF]

, 2013
From an intergroup relations perspective, relative group size is associated with the quantity and quality of intergroup contact: more positive contact (i.e., intergroup friendship) supports, and negative contact (i.e., experienced discrimination) hampers,
Agirdag, Alba, Allport, Aronson, Bail, Benner, Binder, Blalock, Blossfeld, Blumer, Branscombe, Brown, Cohen, Derks, Dixon, Durkin, Eccles, Eller, Fischer, Garcia Coll, Graham, Graham, Hanish, Hanushek, Heath, Herzog-Punzenberger, Hu, Janssens, Jenkins, Juvonen, Kline, Konan, Kristen, Laar, Levin, Longshore, Massey, Matsumoto, McGlothlin, Mendoza-Denton, Mendoza-Denton, Musterd, Muthén, Muthén, Nesdale, Pettigrew, Pettigrew, Pettigrew, Phinney, Phinney, Portes, Postmes, Purdie-Vaughns, Quillian, Rumberger, Saguy, Schofield, Schwarzer, Segregation in School, Shook, Stearns, Swart, Tezanos-Pinto, The Integration of European Second-Generation Survey Austria, The Integration of European Second-Generation Survey Belgium, Thernstrom, Tropp, Verkuyten, Wagner, Walton, Wong, Wright   +71 more
core   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source