Results 41 to 50 of about 1,208,900 (310)

An integrated microbiome-drug interaction and bioinformatics approach identifies active deglycosylated and glycosidic chain metabolites of Platycodin D targeting PTPN2/HIF1A in acute lung injury

Biology Direct
Background Platycodin D (PD) is a typical triterpenoid saponin with low oral bioavailability. Despite its potent anti-ALI effects, its active metabolites and underlying mechanisms remain unclear, thereby significantly impeding its further development ...
Yuanhan Zhong, Yu Peng, Shouwen Zhang, Liyun Wen, Guangpeng Liu, Bingbing Xu, Yonghong Liang, Huiliang Huang, Junwei He, Yong Feng, Jinxiang Zeng, Jian Liang   +11 more
doaj   +1 more source

Herbal plants traded at the Kaili medicinal market, Guizhou, China

Journal of Ethnobiology and Ethnomedicine, 2021
Background Marketplaces reflect not only the commerce of an area, but also its culture. In Qiandongnan Miao and Dong Autonomous Prefecture with Kaili as its capital, Guizhou Province, China, traditional medicine is thriving in both rural and urban areas.
Sizhao Liu, Beixi Zhang, Jiangju Zhou, Qiyi Lei, Qiong Fang, Edward J. Kennelly, Chunlin Long   +6 more
doaj   +1 more source

Discovering genetic diversity of Changmaogu, a rice landrace, for conservation and rural development

Italian Journal of Agronomy, 2021
Changmaogu is a very rare and endangered rice landrace cultivated in a very limited area by Lama people, a branch of Bai ethnic group in Lanping County, Yunnan, China. No study on this precious landrace had been reported.
Liu He, Yingjie Song, Xiufang Liu, Qi Kang, Chunlin Long   +4 more
doaj   +1 more source

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Pharmacokinetic Analysis of Four Bioactive Iridoid and Secoiridoid Glycoside Components of Radix Gentianae Macrophyllae and Their Synergistic Excretion by HPLC-DAD Combined with Second-Order Calibration

Natural Products and Bioprospecting, 2017
An HPLC-DAD method combined with second-order calibration based on the alternating trilinear decomposition (ATLD) algorithm with the aid of region selection was developed to simultaneously and quantitatively characterize the synergistic relationships and
Tian-Ming Yang, Yang-Xi Liu, Hai-Yan Fu, Wei Lan, Han-Bo Su, He-Bin Tang, Qiao-Bo Yin, He-Dong Li, Li-Ping Wang, Hai-Long Wu   +9 more
doaj   +1 more source

Accurate Traceability of Stable C, H, O, N Isotope Ratios and Multi-Element Analysis Combined with Chemometrics for Chrysanthemi Flos ‘Hangbaiju’ from Different Origins

Chemosensors, 2022
Chrysanthemi Flos ‘Hangbaiju’ (HBJ) is a common Chinese medicinal material with the same origin as the medicinal and edible cognate plant in China, whose quality is seriously affected by the place of origin.
Xiuyun Bai, Hengye Chen, Wanjun Long, Wei Lan, Siyu Wang, Guanghua Lei, Yuting Guan, Jian Yang, Haiyan Fu   +8 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Association of Care at Minority-Serving vs Non–Minority-Serving Hospitals With Use of Palliative Care Among Racial/Ethnic Minorities With Metastatic Cancer in the United States

JAMA Network Open, 2019
This cohort study uses data from the National Cancer Database to assess the association between receipt of treatment at minority-serving vs non–minority-serving hospitals and use of palliative care among racial/ethnic minorities with cancer.
A. Cole, D. Nguyen, Akezhan Meirkhanov, M. Golshan, N. Melnitchouk, S. Lipsitz, K. Kilbridge, A. Kibel, Zara Cooper, J. Weissman, Q. Trinh   +10 more
semanticscholar   +1 more source

Biocultural profiles of Qinghai Regong Thangka

Guangxi Zhiwu, 2023
The loss of biodiversity not only means the loss of genes, species and ecosystems, but also threatens the human cultural diversity. Thangka is known as the ‘encyclopaedia’ of traditional Tibetan culture, covering social, historical, cultural, religious ...
Chen LIN, Zhuo CHENG, Chunlin LONG
doaj   +1 more source