Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá +4 more
wiley +1 more source
Triplet Acetone Generation by Pseudoperoxidase Activity of Myoglobin: Structural Damage and Quenching. [PDF]
Gomes TMV +4 more
europepmc +1 more source
Oxaziridines: Versatile Reagents in Modern Organic Synthesis
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra +2 more
wiley +1 more source
Preparation and pharmacological study of <i>Cnidium monnieri</i> volatile oil cream. [PDF]
Sun T +14 more
europepmc +1 more source
Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim +10 more
wiley +1 more source
Comparative Metabolomics Reveals the Production of Sulfated Metabolites by Human Gut Bacteria. [PDF]
D'Agostino GD +9 more
europepmc +1 more source
ABSTRACT This study assessed the ecotoxicological effects of treated sewage on the freshwater planarian Girardia tigrina, integrating biochemical, energetic, and behavioral biomarkers. Planarians were exposed for 48 h to different concentrations of treated sewage (12.5%, 25%, 50%, and 100%) and compared to controls using commercial water and water from
Renata M. P. Freitas +3 more
wiley +1 more source
Practical Enantioselective Approach to 3-Amino-2-Hydroxy Acids and Application to the Synthesis of Natural Products. [PDF]
Caporale M +4 more
europepmc +1 more source
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho +7 more
wiley +1 more source
Serum and Urine Metabolite Profiling Combined With Network Pharmacology to Predict the Renoprotective Mechanism of Huangkui Capsule Against Acute Kidney Injury. [PDF]
Shi JJ +5 more
europepmc +1 more source

