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Structure-Guided Optimization of Novel Inhibitors of <i>Plasmodium</i> Lysyl-tRNA Synthetase with Multistage Activity against Malaria Parasites. [PDF]

open access: yesJ Med Chem
Forte B   +68 more
europepmc   +1 more source
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Formation and inhibition of ethyl glucuronide and ethyl sulfate

Forensic Science International, 2016
Ethyl glucuronide (EtG) und ethyl sulfate (EtS) are widely accepted biomarkers in forensic and clinical settings. Even though, levels of EtG and EtS in blood and urine increase with increasing doses of alcohol, a high inter-individual variability in their production has been noticed.
Nicole, Stachel, Gisela, Skopp
exaly   +3 more sources

Ethyl glucuronide and ethyl sulfate in autopsy samples 27 years after death

International Journal of Legal Medicine, 2008
The unique case of a 50-year-old known alcoholic whose corpse was exhumed 27 years after death is reported. The man apparently committed suicide by hanging, but many years later the case was questioned and homicide-linked to a long-lasting serial killer case-was suspected.
Francesco Mari   +2 more
exaly   +5 more sources

A Comparison of Two Alcohol Biomarkers in Clinical Practice: Ethyl Glucuronide Versus Ethyl Sulfate

Journal of Addictive Diseases, 2013
This study compared the characteristics of two direct alcohol biomarkers, ethyl glucuronide and ethyl sulfate. Both biomarkers were analyzed from urine specimens submitted by 58 active duty service members at Walter Reed National Military Medical Center's Addiction Treatment Service.
R Gregory Landé
exaly   +3 more sources

Nitrosation of arenes with nitrosonium ethyl sulfate

Russian Chemical Bulletin, 1999
Nitrosonium ethyl sulfate reacts withO-alkylphenols andN,N-dialkylanilines to give the corresponding 4-nitrosoarenes. The reaction is not accompanied by side processes characteristic of common nitrosating agents. Diazotization of primary aromatic amines with nitrosonium ethyl sulfate yields stable diazonium salts, which are promising reagents for ...
A N Khlobystov
exaly   +2 more sources

Computer assisted modeling of ethyl sulfate pharmacokinetics

Forensic Science International, 2010
For 12 volunteers of a drinking experiment the concentration-time-courses of ethyl sulfate (EtS) and ethanol were simulated and fitted to the experimental data. The concentration-time-courses were described with the same mathematical model as previously used for ethyl glucuronide (EtG).
Wolfgang Weinmann   +2 more
exaly   +4 more sources

Ethyl glucuronide and ethyl sulfate in meconium and hair-potential biomarkers of intrauterine exposure to ethanol

Forensic Science International, 2010
This study investigated ethyl glucuronide (EtG) and ethyl sulfate (EtS) concentration in meconium and in maternal and neonatal hair (HEtG and HFAEEs, respectively) as potential markers of intrauterine exposure to ethanol together with meconium fatty acid ethyl esters (FAEEs) in a cohort of 99 mother-infant dyads, 49 coming from the Arcispedale of ...
Simona Pichini   +2 more
exaly   +4 more sources

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