Results 1 to 10 of about 6,596 (177)

One-pot H/D exchange and low-coordinated iron electrocatalyzed deuteration of nitriles in D2O to α,β-deuterio aryl ethylamines [PDF]

open access: yesNature Communications, 2022
One-pot efficient synthesis of α,β-deuterio aryl ethylamines with high deuterium ratios using an easy-to-handle deuterated source under ambient conditions is desirable.
Rui Li   +5 more
doaj   +3 more sources

Reductive Methylation of Homogeneous Primary β-Lauryl/myristyl 7/3 Polyethyleneoxy n = 3–18 Ethylamines under Phase-Transfer Catalysis Conditions [PDF]

open access: yesMolecules, 2021
Homogeneous tertiary N,N-dimethyl-N-β-lauryl/myristyl 7/3 polyethyleneoxy n = 3–18 ethylamines, LM(EO)nAT, are niche intermediates in the synthesis of homogeneous N-alkyl (C1–C18)-N,N-dimethyl-N-β-lauryl/myristyl 7/3 polyethyleneoxy n = 3–18 ...
Călin Jianu
doaj   +2 more sources

Study on the Interaction between Curcumin and Ethylamines by Absorption and Fluorescence Spectroscopic Techniques

open access: yesTextile Coloration and Finishing, 2015
The interaction between curcumin(1,7-bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) and ethylamines was studied in DMSO:H 2 O(5:1, v/v) using absorption and fluorescence measurements.
Jin-Seok Bae, Eun-Mi Lee
exaly   +2 more sources

Synthesis of dichloroacetamides and study of their anti-tumor activity

open access: yesФармацевтичний журнал, 2022
Dichloroacetic acid and its derivatives exhibit the properties of metabolic cytoprotectors and apoptosis inducers. Nowadays evaluation of these derivatives is being conducted regarding the induction of immunogenic cell death.
L. M. Havryshchuk   +2 more
doaj   +1 more source

Electrochemical reduction of acetonitrile to ethylamine [PDF]

open access: yesNature Communications, 2021
AbstractElectrifying chemical manufacturing using renewable energy is an attractive approach to reduce the dependence on fossil energy sources in chemical industries. Primary amines are important organic building blocks; however, the synthesis is often hindered by the poor selectivity because of the formation of secondary and tertiary amine byproducts.
Rong Xia   +7 more
openaire   +4 more sources

Parallel Synthesis of 2-Substituted 6-(5-Oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides

open access: yesMolecules, 2012
A library of 24 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides <strong>10</strong>{<em>1</em>,<em>2</em>; <em>1–12</em>} was prepared by a parallel solution-phase approach.
Branko Stanovnik   +6 more
doaj   +1 more source

Catalytic Enantioselective Synthesis of α-Chiral Azaheteroaryl Ethylamines by Asymmetric Protonation.

open access: yesAngewandte Chemie, 2018
The direct enantioselective synthesis of chiral azaheteroaryl ethylamines from vinyl-substituted N-heterocycles and anilines is reported. A chiral phosphoric acid (CPA) catalyst promotes dearomatizing aza-Michael addition to give a prochiral exocyclic ...
Chao-Fan Xu   +4 more
semanticscholar   +1 more source

Synthesis of novel amide and urea derivatives of thiazol-2-ethylamines and their activity against Trypanosoma brucei rhodesiense

open access: yesBioorganic & Medicinal Chemistry, 2016
2-(2-Benzamido)ethyl-4-phenylthiazole (1) was one of 1035 molecules (grouped into 115 distinct scaffolds) found to be inhibitory to Trypanosoma brucei, the pathogen causing human African trypanosomiasis, at concentrations below 3.6 μM and non-toxic to ...
D. A. Patrick   +6 more
semanticscholar   +1 more source

Bis‐Naphthyl Dipicolinic Dicarboxamide‐Based Self‐Assembled Aqueous Nano Dispersion as an Efficient Light Harvesting Medium and Cucurbit[7]Uril Host Complexation Effect Study

open access: yesAdvanced Optical Materials, EarlyView.
Bis‐naphthyl‐4‐hydroxy‐dipicolinic‐dicarboxamide, a small molecule, forms nanodispersion as an efficient light‐harvesting medium in aqueous solution. Further cucurbit[7]uril addition was found to inhibit the FRET co‐assembly by host‐guest complexation. ABSTRACT Development of artificial light harvesting systems in a minimalistic self‐assembly model is ...
Tumpa Gorai   +2 more
wiley   +1 more source

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

open access: yesAdvanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng   +9 more
wiley   +1 more source

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