Results 31 to 40 of about 107,774 (301)

Effect of continuous soft chelating irrigation protocol on removal of smear layer

Endodontology, 2019
Aim: The purpose of this study was to compare the efficacy of continuous soft chelating irrigation protocol with conventional irrigation protocol. Methodology: sixty extracted single-rooted human teeth were randomly divided into 5 groups (n =12) and ...
Vibha Hegde, Pranav Thakkar
doaj   +1 more source

Effect of stabilizer EDTA on the thermal hazard of green synthesis process of adipic acid and development of microchannel continuous flow process

Emergency Management Science and Technology, 2023
In the green synthesis reaction of adipic acid, the oxidant H2O2 undergoes exothermic decomposition easily and the high exothermic amount of the reaction can easily lead to thermal runaway.
Weidong He, Yuanyuan Li, Lei Ni, Wen Zhu
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Comparative evaluation of depth of penetration of sealer after using EDTA, citric acid and R-EDTA as last irrigant under confocal laser microscopy

Endodontology
Aim: This original research examines potential of root canal sealers to penetrate the dentin. Movement of root canal sealer into dentinal tubules decreases the residual space for the entombing of bacteria and provides the hermetic seal.
Asit Vats, Arundeep Singh
doaj   +1 more source

Determination of EDTA in dairy wastewater and adjacent surface water [PDF]

, 2008
—An HPLC-UV analytical method was developed to determine ethylenediaminetetraacetic acid (EDTA) in dairy wastewater and surface water. The optimizing separation was achieved by reversed–phase ion-pair liquid chromatography on a C18 column using methanol ...
Xie, Congmin Z., Robinson, Peter, Healy, Terry, Stewart, Kevin   +3 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Supplemental Figure 1: A rapid and sensitive method to measure numbers of live cells in alginate capsules following depolymerization with ethylenediaminetetraacetic acid

, 2023
Supplemental Figure 3: A rapid and sensitive method to measure numbers of live cells in alginate capsules following depolymerization with ethylenediaminetetraacetic acid 
Martin Grumet (15366268), Maciej Kabat (15366262), Ivan Bobkov (15366265)   +2 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Ethylenediaminetetraacetic Acid Inhibits Vibrio Vulnificus-Induced Dendritic Cell Apoptosis by Lowering [Ca2+]i

Neurosignals, 2018
Background/Aims: Vibrio vulnificus (V. vulnificus) is a Gram-negative marine bacterium that can cause life-threatening primary septicemia, especially in the innate immune system. But how V.
Ping Qian, Bo Hu, Yuzhang Zhu, Dongliang Shao, Huaifeng Zhang, Huafei Huang, Lizhong Wang, Ruilin Shen   +7 more
doaj   +1 more source