Results 101 to 110 of about 1,913,301 (392)

The N6-Methyladenosine Features of mRNA and Aberrant Expression of m6A Modified Genes in Gastric Cancer and Their Potential Impact on the Risk and Prognosis

Frontiers in Genetics, 2020
Although N6-methyladenosine (m6A) mRNA methylation is known to be closely related to tumor events, its role in carcinogenesis and the development of gastric cancer (GC) is not yet clear. The aim of this study was to identify common m6A features and novel
Liang Sang, Liang Sang, Liping Sun, Liping Sun, Liping Sun, Ang Wang, Ang Wang, Ang Wang, Han Zhang, Han Zhang, Han Zhang, Yuan Yuan, Yuan Yuan, Yuan Yuan   +13 more
doaj   +1 more source

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source

A study of the etiology of referred Otalgia [PDF]

, 2012
Introduction: Otalgia is one of the complaints which may occur at any age. The etiology of the pain may be in the ear, structures around the ear or other head and neck structures.
Behnampour, N., Taziki, M.H.
core   +1 more source

Carbohydrate Intake in the Etiology of Crohn's Disease and Ulcerative Colitis [PDF]

, 2014
Background: Diet may have a role in the etiology of inflammatory bowel disease. In previous studies, the associations between increased intakes of carbohydrates, sugar, starch, and inflammatory bowel disease are inconsistent.
Abraham, Amre, Andrew R. Hart, Anja Olsen, Anne Tjonneland, Antoine Racine, Antonia Trichopoulou, Bas Oldenburg, Bennett, Bernstein, Bianchi Porro, Bingham, Bohlscheid-Thomas, Calkins, Chan, Darmon, De Filippo, Domenico Palli, Essebag, Fiona van Schaik, Francesca L. Crowe, Franck Carbonnel, Gaboriau-Routhiau, Geerling, Giovanna Masala, Göran Hallmans, H. Bas Bueno-de-Mesquita, Hart, Heresbach, Hou, Iwaya, Jantchou, Jarnerot, Jostins, Kaaks, Kasper, Katsouyanni, Kay-Tee Khaw, Kim Overvad, Kurakevich, Kurata, Maconi, Manuela M. Bergmann, Margetts, Marie-Christine Boutron-Ruault, Martinez-Medina, Maslowski, Mendall, Moreno-Navarrete, Ocke, Olof Grip, Orholm, Peeters, Persson, Pisani, Pontus Karling, Poullis, Prynne, Quezada, Reif, Riboli, Riboli, Robert Luben, Rosario Tumino, Rudolf Kaaks, Sakamoto, Sartor, Satsangi, Shivananda, Silkoff, Simon S. M. Chan, Slimani, Sonnenberg, Spooren, Stefan Lindgren, Thia, Thornton, Timothy Key, Tjonneland, Tragnone, Turnbaugh, van Liere, Wen, Zhang   +83 more
core   +1 more source

Expression and prognostic potential of ribosome 18S RNA m6A methyltransferase METTL5 in gastric cancer

Cancer Cell International, 2021
Background Ribosomal RNA N6-methyltransferase METTL5 was reported to catalyze m6A in 18S rRNA. We aimed to investigate the expression and prognostic features of METTL5 in gastric cancer (GC). Methods In this study, 168 GC patients and their corresponding
Zhenshuang Wang, Jingwei Liu, Yi Yang, Chenzhong Xing, Jingjing Jing, Yuan Yuan   +5 more
doaj   +1 more source

Etiology and Pharmacology of Neuropathic Pain

Pharmacological Reviews, 2018
Injury to or disease of the nervous system can invoke chronic and sometimes intractable neuropathic pain. Many parallel, interdependent, and time-dependent processes, including neuroimmune interactions at the peripheral, supraspinal, and spinal levels ...
Sascha R. A. Alles, Peter A. Smith
semanticscholar   +1 more source

Genetic Profile and Symptom Pattern Explain Variability of Deep Brain Stimulation Effect in Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Bilateral globus pallidus pars interna deep brain stimulation (GPi‐DBS) is a recognized and effective treatment option for drug‐resistant dystonia patients. However, the clinical GPi‐DBS outcomes vary significantly. Herein, we explored the pre‐implant factors affecting GPi‐DBS effectiveness.
Mahboubeh Ahmadipour, Luigi M. Romito, Antonio E. Elia, Nico Golfré Andreasi, Roberto Eleopra, Alberto Mazzoni, Fabiana Colucci   +6 more
wiley   +1 more source

Prevalence, incidence and etiology of hyponatremia in elderly patients with fragility fractures [PDF]

, 2014
Peer reviewedPublisher ...
Cumming, Kirsten, Hoyle, Graeme E, Hutchison, James D, Soiza, Roy L   +3 more
core   +3 more sources

Antimicrobial activity of red wine and oenological extracts against periodontal pathogens in a validated oral biofilm model

BMC Complementary and Alternative Medicine, 2019
Background Previous research findings support an antimicrobial effect of polyphenols against a variety of pathogens, but there is no evidence of this effect against periodontal pathogens in complex biofilms.
María C. Sánchez, Honorato Ribeiro-Vidal, Adelaida Esteban-Fernández, Begoña Bartolomé, Elena Figuero, María V. Moreno-Arribas, Mariano Sanz, David Herrera   +7 more
doaj   +1 more source

Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis

Nature Communications, 2021
Esophageal squamous-cell carcinomas (ESCC) have poor prognosis, and detailed molecular profiles are necessary to identify prognostic markers. Here the authors analyse 60 ESCC patient samples using scRNA-seq, TCR-seq and genomics; they find mucosal ...
Xiannian Zhang, Linna Peng, Yingying Luo, Shaosen Zhang, Yang Pu, Yamei Chen, Wenjia Guo, Jiacheng Yao, Mingming Shao, Wenyi Fan, Qionghua Cui, Yiyi Xi, Yanxia Sun, Xiangjie Niu, Xuan Zhao, Liping Chen, Yuqian Wang, Yachen Liu, Xinyu Yang, Chengcheng Wang, Ce Zhong, Wen Tan, Jianbin Wang, Chen Wu, Dongxin Lin   +24 more
doaj   +1 more source