Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim +11 more
wiley +1 more source
Granulomatous Lung Inflammation of Unknown Causes Following COVID-19. [PDF]
Watanabe K, Kaneko T.
europepmc +1 more source
Clinical and Laboratory Characterization of Acquired Von Willebrand Syndrome
ABSTRACT Acquired von Willebrand Syndrome (AVWS) is a rare bleeding disorder characterized by quantitative or qualitative defects of von Willebrand factor (VWF) in patients without a personal or family history of bleeding. It is frequently associated with systemic diseases, particularly lymphoproliferative disorders (LPDs) and myeloproliferative ...
Alessandro Ciavarella +10 more
wiley +1 more source
Temporal changes in etiology, complications, and infection-related admissions among patients with cirrhosis: a 20-year single-center study. [PDF]
Su R, Yao W, Mian Y, Zhang Y, Yang S.
europepmc +1 more source
ABSTRACT People with Phelan–McDermid syndrome (PMS) have reduced speech and language abilities, yet little research has profiled the communication abilities in this population. The purpose of this study was threefold: identifying the language and communication profiles of school‐aged children with PMS, identifying genetic contributions to language and ...
Sarah Quadri‐Valverde +12 more
wiley +1 more source
Nitroso compounds: Biological mechanisms, exposures and cancer etiology
O'Neill, I.K., Bartsch, H.
core
Associations Between Elevated Anticardiolipin IgG, Thrombocytopenia, and Combined Diabetes-Hypertension Etiology in Hemodialysis Patients. [PDF]
Makhdoom HQ +7 more
europepmc +1 more source
The 9th International RASopathies Symposium
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
Ablation timing in ECMO-supported electrical storm: one strategy does not fit all substrates. [PDF]
Guinot PG, Guenancia C.
europepmc +1 more source
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman +15 more
wiley +1 more source

