Results 191 to 200 of about 20,342 (251)
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Etomidate as an induction agent for endotracheal intubation in critically ill patients: A meta-analysis of randomized trials.

Journal of critical care, 2023
PURPOSE We performed a meta-analysis of randomized controlled trials to evaluate if etomidate impacted mortality in critically ill adults when compared with other induction agents.
Y. Kotani   +8 more
semanticscholar   +1 more source

The Effect of Ketamine Versus Etomidate for Rapid Sequence Intubation on Maximum Sequential Organ Failure Assessment Score: A Randomized Clinical Trial.

Journal of Emergency Medicine, 2023
BACKGROUND The use of induction agents for rapid sequence intubation (RSI) has been associated with hypotension in critically ill patients. Choice of induction agent may be important and the most commonly used agents are etomidate and ketamine ...
S. Knack   +6 more
semanticscholar   +1 more source

Etomidate revisited

Current Opinion in Anaesthesiology, 1998
The major advantage of etomidate is its lack of cardiovascular side effects. In addition, etomidate is supposed to be neuroprotective. The side effects of etomidate include adrenal suppression and myocloni. A review of the recent literature on etomidate, its clinical use, its side effects and its mechanism of action was performed.
P, Ostwald, A W, Doenicke
openaire   +2 more sources

Determination of etomidate and etomidate acid in hair using liquid chromatography–tandem mass spectrometry

Journal of Forensic Sciences, 2022
Etomidate, with efficacy similar to that of propofol, has been used as a propofol substitute because propofol is a designated narcotic drug, and an increase in the frequency of illegal distribution and misuse has been reported in Korea.
Y. J. Park   +10 more
semanticscholar   +1 more source

Etomidate elicits anti-tumor capacity by disrupting the JAK2/STAT3 signaling pathway in hepatocellular carcinoma.

Cancer Letters, 2022
Hepatocellular carcinoma (HCC) is a leading malignancy of the digestive system, especially in China. Although radiotherapy, chemotherapy, and transarterial chemoembolization have achieved tremendous success, surgical resection remains the primary ...
Jiali Xu   +12 more
semanticscholar   +1 more source

Etomidate-Induced Myoclonus in Sprague-Dawley Rats Involves Neocortical Glutamate Accumulation and N-Methyl-d-Aspartate Receptor Activity

Anesthesia and Analgesia, 2022
BACKGROUND: Etomidate-induced myoclonus, a seizure-like movement, is of interest to anesthetists. However, its origin in the brain and its underlying mechanism remain unclear.
Yan Feng   +6 more
semanticscholar   +1 more source

Hemodynamics in Helicopter Emergency Medical Services (HEMS) Patients Undergoing Rapid Sequence Intubation With Etomidate or Ketamine.

Journal of Emergency Medicine, 2022
BACKGROUND Rapid sequence intubation (RSI) is performed by helicopter emergency medical services (HEMS) providers to establish airway control. Common induction agents are etomidate and ketamine, both touted to have relatively stable hemodynamic profiles.
S. Kunkel, T. Lenz
semanticscholar   +1 more source

Fast and reliable analysis of veterinary metomidate and etomidate in human blood samples by liquid chromatography–tandem mass spectrometry (LC–MS/MS) in a postmortem case

Journal of Forensic Sciences, 2021
Metomidate and etomidate belong to the non‐barbiturate imidazole family of sedative–hypnotics and elicit little analgesic action when used alone. Metomidate, in particular, has little analgesic activity in humans and is, therefore, used for veterinary ...
Hyesun Yum   +10 more
semanticscholar   +1 more source

Etomidate in Severe Cushing Syndrome: A Systematic Review

Journal of the Endocrine Society
Background Severe Cushing syndrome is a medical emergency. Etomidate is the only IV option available for treating hypercortisolism, especially in critically ill patients obviating oral medications.
D. Muthukuda   +7 more
semanticscholar   +1 more source

Metabolic Profile of Etomidate and Its Three Analogs in Zebrafish, Human Liver Microsomes, Human Urine and Hair Samples Using UHPLC-Q Exactive Orbitrap-HRMS.

Drug Testing and Analysis
Etomidate is a short-acting non-barbiturate imidazole used as an intravenous anesthetic agent in humans, while metomidate and propoxate are common anesthetic drug for fishes.
Yiling Tang   +6 more
semanticscholar   +1 more source

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