Results 201 to 210 of about 20,342 (251)

Ketamine Versus Etomidate for Rapid Sequence Intubation: A Systematic Review and Meta-Analysis of Randomized Trials

Critical Care Medicine
OBJECTIVES: To compare the safety and efficacy of ketamine and etomidate as induction agents to facilitate emergent endotracheal intubation. DATA SOURCES: We searched MEDLINE, Embase, Cochrane Clinical Trials Register, and ClinicalTrials.gov from ...
Alisha Greer, M. Hewitt, Parsa T. Khazaneh, B. Ergan, L. Burry, M. Semler, B. Rochwerg, S. Sharif   +7 more
semanticscholar   +1 more source

Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine Among Critically Ill Patients.

American Journal of Respiratory and Critical Care Medicine
RATIONALE Uncertainty remains regarding the risks associated with single dose use of etomidate. OBJECTIVES To assess use of etomidate in critically ill patients and compare outcomes for patients who received etomidate versus ketamine.
Hannah Wunsch, N. Bosch, A. Law, E. Vail, May Hua, B.H. Shen, P. Lindenauer, David N. Juurlink, Allan J Walkey, H. Gershengorn   +9 more
semanticscholar   +1 more source

Physical and Chemical Compatibility of Etomidate and Propofol Injectable Emulsions

Pharmacology, 2021
Introduction: The mixture of etomidate and propofol is widely used in clinical practice to improve efficacy of general anesthesia and to minimize side effects.
Chunping Wang, Shengnan Wang, Cui-shuan Wu, Linkuo Lei, Dong-Xin Wang, Qiang Zhang   +5 more
semanticscholar   +1 more source

The Application and Pharmaceutical Development of Etomidate: Challenges and Strategies.

Molecular Pharmaceutics
Etomidate is a synthetic imidazole anesthetic that exerts hypnotic effects by potentiating the action of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) or directly activating the anionic GABA (GABAA) receptor.
Hao Zhang, Ailing Wu, Xichen Nan, Luhan Yang, Dan Zhang, Zhuo Zhang, Hao Liu   +6 more
semanticscholar   +1 more source

Characterization of etomidate and emerging analogs in human hair using UHPLC-MS/MS and confirmation in real forensic cases.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
The regulation of etomidate, a widely used drug for anesthesia induction and short surgical procedures, has led to the emergence of etomidate analogs such as metomidate, propoxate, and isopropoxate.
Lina Pei, Shuo Yang, Chaodan Cui, Xin Wang, Ping Xiang, Yonghui Dang, Yan Shi   +6 more
semanticscholar   +1 more source

Etomidate as an anesthetic in Colossoma macropomum: Behavioral and electrophysiological data complement each other as a tool to assess anesthetic safety

PLoS ONE
The use of anesthetic agents in the management of fish in fish farming or ornamental fish breeding aims to minimize stress and promote animal welfare.
T. Reis, Daniella Bastos de Araújo, C. Paz, Rodrigo Gonçalves Santos, A. Barbosa, L. Souza, Yris da Silva Deiga, Vera Louzeiro de Oliveira Garcia, G. Barbosa, Lucas Lima da Rocha, Moisés Hamoy   +10 more
semanticscholar   +1 more source

Detection of "smoke powder" etomidate and its metabolite etomidate acid in blood and urine by UHPLC-MS/MS: Application in authentic cases.

Journal of Analytical Toxicology
Recently, etomidate has been widely used as an alternative in illicit drug market. It is usually added to regular cigarette tobacco (commonly known as "cigarette powder") or mixed in e-cigarette oil sold through the Internet, retail stores, or ...
Liying Zhou, Junbo Zhao, Wanting Xie, Ping Xiang, Yan Shi, He-jian Wu, Hui Yan   +6 more
semanticscholar   +1 more source

Etomidate, Adrenal Insufficiency and Mortality Associated With Severity of Illness: A Meta-Analysis

Journal of Intensive Care Medicine, 2020
Purpose: Etomidate causes adrenal insufficiency. Yet in critically ill patients, it is controversial whether it increases mortality rates above that of comparator anesthetic induction agents. We postulated that etomidate would increase relative mortality
S. Albert, S. Sitaula
semanticscholar   +1 more source

Etomidate

Reactions Weekly, 2012
François, Lauzier, Alexis F, Turgeon
  +6 more sources

KEtaminE/ProPofol Admixture vs Etomidate for Intubation in the Critically-Ill: KEEP PACE Randomized Clinical Trial.

Journal of Trauma and Acute Care Surgery, 2019
BACKGROUND Peri-intubation hypotension is associated with poor outcomes in the critically-ill. We aimed to determine if an admixture of ketamine and propofol for emergent endotracheal intubation in critically-ill patients was superior to etomidate ...
N. Smischney, W. Nicholson, Daniel R. Brown, A. D. De Moraes, S. Hoskote, B. Pickering, R. Oeckler, V. Iyer, O. Gajic, D. Schroeder, P. Bauer   +10 more
semanticscholar   +1 more source