Results 121 to 130 of about 89,048 (269)

Induction of senescence by etoposide.

open access: yes, 2013
(A) NRK-52E cells were treated with 1 µg/ml etoposide (Etop) for 3 days and subjected to phase-contrast microscopy and SA-β-gal staining. (B–D) Quantitative assessment of senescent morphology (B), positive staining for SA-β-gal (C) and viable cell number
Masanori Kitamura (19679)   +1 more
core   +1 more source

Clinical features and prognostic factors of adult systemic chronic active EBV disease: A retrospective analysis in Japan

open access: yesBritish Journal of Haematology, EarlyView.
ALT and ferritin were adverse prognostic markers enabling risk stratification in adult systemic chronic active Epstein–Barr virus disease (sCAEBV). In hydroa vacciniforme lymphoproliferative disorder (HV‐LPD), Epstein–Barr virus (EBV) infection of CD4+ cells was associated with progression to sCAEBV.
Aika Fuseya   +15 more
wiley   +1 more source

Response‐adapted consolidation and salvage strategies in secondary central nervous system lymphoma: Insights from a multicentre cohort

open access: yesBritish Journal of Haematology, EarlyView.
Summary Secondary central nervous system lymphoma (SCNSL) remains a rare but challenging manifestation of aggressive lymphomas, with limited prospective data to guide treatment decisions in the modern therapeutic era. We conducted a multicentre retrospective cohort study of 105 consecutively treated adult patients diagnosed with SCNSL between 2016 and ...
Farina Eigendorff   +10 more
wiley   +1 more source

Unveiling CKS2: A Key Player in Aggressive B‐Cell Lymphoma Progression and a Target for Synergistic Therapy

open access: yesCancer Medicine
Background The objective of this study was to investigate the expression levels and biological significance of CKS2 in Burkitt cell lymphoma (BL) and diffuse large B‐cell lymphoma (DLBCL).
Fenling Zhou   +6 more
doaj   +1 more source

Des1 ablation protects from etoposide-induced apoptosis.

open access: yes, 2012
A. MTS assay showing percent metabolic viability after treating Des1+/+ and Des1−/− cells with 20 µM etoposide at 24 hours and 48 hours of post-treatment. MTS assay measures metabolic viability that also indicates cell viability.
Scott A. Summers (136747)   +7 more
core   +1 more source

Diagnosis and management of neutropenia in adults: Expert guidance

open access: yesBritish Journal of Haematology, EarlyView.
Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte   +5 more
wiley   +1 more source

Secondary leukaemia after testicular germ cell tumour treatment: a systematic review and meta‐analysis

open access: yesBJU International, EarlyView.
Background Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15–35 years. Management options for men with TGCTs include surgery, radiation and/or chemotherapy, depending on stage. Given TGCTs’ excellent survival, most patients live long enough to experience delayed treatment toxicities, warranting careful consideration of ...
Ahmad Mousa   +5 more
wiley   +1 more source

Acute Dystonia from Etoposide

open access: yes, 1988
We present a case of acute dystonia caused by administration of etoposide in an 11-year-old boy being treated for acute lymphoblastic leukemia. We believe this is the first report of this side effect.
Robert A. Delaney, David P. Ascher
core   +1 more source

Intercalating compounds alongside DNA helicase Q1 Plasmodium falciparum 3D7: Assessments of pharmacokinetic properties prediction of ADME

open access: yesJournal of Vector Borne Diseases
Background & objectives: Quantum chemical and molecular docking practices deliver new perceptions into how etoposide, novobiocin, nogalamycin and netropsin interact with the biological targets PF3D7_0918600 (Plasmodium falciparum 3D7).
Afnan Shakoori   +8 more
doaj   +1 more source

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