Results 71 to 80 of about 3,437 (296)

Who rules the waves? : governance and new institutional arrangements in Dutch fisheries management in the context of the European common fisheries policy

, 2010
Top down government ruling is perceived as a main contributor to the failure of fisheries management. A change in the governance set up, with a more participatory signature and a change in role and position of the state, the industry and society in ...
van Hoof, L.J.W., Hoof, L.J.W., van
core  

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

The seascape of demersal fish nursery areas in the North Mediterranean Sea, a first step towards the implementation of spatial planning for trawl fisheries.

PLoS ONE, 2015
The identification of nursery grounds and other essential fish habitats of exploited stocks is a key requirement for the development of spatial conservation planning aimed at reducing the adverse impact of fishing on the exploited populations and ...
Francesco Colloca, Germana Garofalo, Isabella Bitetto, Maria Teresa Facchini, Fabio Grati, Angela Martiradonna, Gianluca Mastrantonio, Nikolaos Nikolioudakis, Francesc Ordinas, Giuseppe Scarcella, George Tserpes, M Pilar Tugores, Vasilis Valavanis, Roberto Carlucci, Fabio Fiorentino, Maria C Follesa, Magdalena Iglesias, Leyla Knittweis, Eugenia Lefkaditou, Giuseppe Lembo, Chiara Manfredi, Enric Massutí, Marie Louise Pace, Nadia Papadopoulou, Paolo Sartor, Christopher J Smith, Maria Teresa Spedicato   +26 more
doaj   +1 more source

Policy Incoherence: EU Fisheries Policy in Senegal [PDF]

human development, aid, trade ...
Oli Brown
core  

Trade Agreements, Multifunctionality and EU Agriculture. CEPS Paperbacks. December 2006 [PDF]

, 2006
This book examines the repercussions of the EU’s agricultural policies and its regional, bilateral and multilateral trade agreements. It presents the analyses and findings of the European Network of Agricultural and Rural Policy Research Institutes ...
dell’Aquila, Crescenzo, Jensen, Hans, Doucha, Tomáš, Psaltopoulos, Demitrios, Hanrahan, Kevin, Salamon, Petra, Pelikan, Janine, Balamou, Eudokia, von Ledebur, Oliver, Dwyer, Janet, Kuiper, Marijke, Niemi, Jyrki, Brockmeier, Martina, Foltýn, Ivan, Yu, Wusheng, Damianos, Dimitris, Baldock, David, Alexopoulos, Yiorgos, Lehtonen, Heikki, Kaditi, Eleni, Guyomard, Hervé, Kurzweil, Marianne, van Tongeren, Frank, Klepper, Rainer, Donnellan, Trevor, Swinnen, Johan, Lankoski, Jussi, Huan-Niemi, Ellen   +27 more
core  

Common Commercial Policy (CCP)

, 2022
Since the early days of the European Union (EU), the Common Commercial Policy (‘CCP’) has been considered as the core competence in the area of the external relations of the EU (Arts 21–46 and 205–22 Treaty on the Functioing of the European Union (TFEU)).
Ziegler, Andreas R.
core  

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

[EU] EU Common Fisheries Policy (CFP)

, 2019
With the latest reform from 2013, the common fisheries policy is the first comprehensive legal framework, featuring attention to the environmental, economic and social dimensions of fisheries fish stock management at maximum sustainable yield by 2020 for
European Commision
core