Results 111 to 120 of about 971,283 (354)

Ideology in the EU’s Second Chamber: A New Understanding of the Character and Impact of the Council on EU Policy Making [PDF]

open access: yes, 2015
This paper examines both the presence and the impact of ideology on the Council of the European Union. It argues that Member States within the Council should not be treated as unitary actors given that in fact, member states are represented by ...
Kreppel, Amie
core  

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Politicizing Council decision-making: The effect of EP empowerment [PDF]

open access: yes, 2009
Research on the intra-institutional consequences of differences in the EU’s inter-institutional rule configurations is rare. This study investigates the effect of the empowerment of the European Parliament (EP) on the active involvement of ministers in ...
Haege, Frank
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

More on the EU Council conclusions

open access: yes, 2007
Tom Tivnan, EU open access push, <em> Bookseller.com </em> , November 28, 2007.
openaire   +1 more source

The Impact of Council’s Internal Decision-Making Rules on the Future EU [PDF]

open access: yes
This paper deals with the voting rules in the EU Council. Both internal and external impact of the voting rules are evaluated. Internal impact affects the distribution of power among the member states and external impact affects power relations between ...
Mika Widgrén
core  

The EU's dialogue on migration, mobility, and security with the Southern Mediterranean: filling the gaps in the global approach to migration. CEPS Liberty and Security in Europe, June 2011 [PDF]

open access: yes, 2011
Recent events in North Africa and the Mediterranean have had consequences in terms of human mobility, and are putting the foundations and components of EU’s migration policy under strain.
Carrera, Sergio.
core  

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