Results 51 to 60 of about 95,849 (219)

COUNCIL REGULATION (EU) 2019/1111: NEW PROGRESS IN INTERNATIONAL CHILD ABDUCTIONS [PDF]

open access: yesChallenges of the Knowledge Society
Council Regulation (EU) 2019/1111, recently entered into force, brought significant progress for EU Member States in the specific area of international child abductions.
Anca Magda VOICULESCU
doaj  

The Problem of Accession of the European Union to the European Convention of Human Rights and Fundamental Freedoms

open access: yesМосковский журнал международного права, 2009
The author considers the problem of human rights protection in the EU, the history of the mentioned issue, as well as why it is necessary for the EU to accede to the European Convention.
I. V. Surodeykina
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Implementation of New EU Directives Coordinating the Procedures for Awarding Public Contracts in European Union Member States: The Example of Poland

open access: yesStudies in Logic, Grammar and Rhetoric, 2020
This article concerns the implementation of new EU Directives coordinating the procedures for awarding public contracts in European Union Member States. In a number of countries, including Poland, the process of their implementation (Directive 2014/24/EU
Radwanowicz-Wanczewska Joanna
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Coherence of European Union Actions at the UN Human Rights Council and the Council of Europe

open access: yesVestnik MGIMO-Universiteta, 2019
The current methodological debates on the EU external actions at international organisations raise the issue of the EU coherence. The scholarship tends to focus on EU vertical and horizontal coherence in various policies, making the EU internal ...
Anatoly Boyashov
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

BREXIT AND THE ROMANIAN PRESIDENCY OF THE COUNCIL OF THE EUROPEAN UNION – LEGAL ASPECTS AND POSSIBILITIES [PDF]

open access: yesChallenges of the Knowledge Society, 2019
The first half of 2019 finds the European Union facing two challenges: the rotating Presidency of the Council of the European Union is held by Romania, one of the newest members of the organisation, while the United Kingdom prepares to withdraw, after ...
Maria-Cristina SOLACOLU
doaj  

How to follow the new EU Council recommendation and improve prostate cancer early detection: the Prostaforum 2022 declaration. [PDF]

open access: yesEur Urol Open Sci, 2023
Májek O   +13 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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