Results 221 to 230 of about 153,871 (338)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

WiNGS-API: a federated genome/phenome data sharing platform enabling gene discovery and variant classification for rare diseases. [PDF]

Genome Med
Sattanathan N, Huremagic B, Vermeesch JR, Moreau Y, Vandeweyer G.   +4 more
europepmc   +1 more source

Analysis of highly radiative scenarios for the EU‐DEMO divertor target protection

, 2018
F. Subba, D. Coster, A.N. Escat Juanes, E. Fable, R. Wenninger, R. Zanino   +5 more
openalex   +2 more sources

Implementation of the EU-DEMO Exhaust Modelling Roadmap

, 2022
Wiesen, S, Aho-Mantila, L, Dasbach, S, Matveev, D, Romazanov, J, Wischmeier, M, Osawa, R, Subba, F:, Coleman, M, Maviglia, F, Siccinio, M, Zohm, H, Bernert, M, Brezinsek, S   +13 more
openaire   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

An abacus for P2P-TV traffic classification [PDF]

, 2009
Bermolen, P., Mellia, Marco, Meo, Michela, Rossi, D., Valenti, S.   +4 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Microstructural Stability of 316 L Produced by Additive Manufacturing for Nuclear Applications. [PDF]

Materials (Basel)
Montanari R, Palombi A, Richetta M, Stornelli G, Varone A, Zahid A.   +5 more
europepmc   +1 more source

Making democracy work: revisions to the EU's European neighbourhood policy would promote democratic reform in North Africa [PDF]

, 2012
Lannon, Erwoan
core   +1 more source

Design Progress of Structural Components of the EU DEMO EC Equatorial Launcher

P. Spaeh, A. Bruschi, R. Chavan, Alexandre Clément, Fabien Crisinel, A. Cufar, F. Fanale, S. Garavaglia, J.-P. Hogge, Avelino Mas Sánchez, Marc Noël, N. Rispoli, D. Strauß, Chuanren Wu   +13 more
openalex   +2 more sources