Results 1 to 10 of about 2,181 (66)
A Biologically Dominant Trophoblastic Component Guiding Neoadjuvant EMA/CO in Endometrial Carcinoma: A Clinical Case Report. [PDF]
ABSTRACT Endometrial carcinoma with choriocarcinomatous components (ECCC) is a rare and aggressive malignancy for which optimal management remains undefined. We report a case illustrating how preoperative identification of a biologically dominant trophoblastic component can guide treatment sequencing and achieve durable remission.
Shirakawa S +15 more
europepmc +2 more sources
Virus‐Mediated Self‐Assembly of Functional Cyclodextrins for Antiviral Inhibition
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Pedro J. Hernando +10 more
wiley +2 more sources
Epimer discrimination remains challenging due to subtle NMR differences. Here, we propose a methodology based on 13C‐RCSA and RDC anisotropic parameters, enabling the assignment of two flexible tetraprenyltoluquinol epimers (1a and 1b) with remote stereoclusters.
Juan Carlos C. Fuentes‐Monteverde +6 more
wiley +2 more sources
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero +7 more
wiley +1 more source
Multiscale numerical sensitivity simulations of a mesoscale gravity‐wave event
High‐resolution WRF simulations of the February 14–15, 1992 STORM‐FEST event show that mesoscale gravity‐wave genesis occurs via geostrophic adjustment within an upper‐level unbalanced jet, while wave ducting governs maintenance. High‐resolution (1 km), improved physical parameterization, and targeted sensitivity simulations demonstrate that upstream ...
Rajan Bhandari +2 more
wiley +1 more source
“Hold on, I'm comin'”: Copyright, political campaigns, and the limits of songwriter control
Abstract This article examines how songwriters in the United States object to the unwanted performance of their musical works at live political events, and the legal options available to challenge such uses. Prompted by the repeated use of ‘Hold On, I'm Comin'’ as outro music at Donald Trump's campaign events between 2020 and 2024, and the recent ...
Joel Cooper, Marie Hadley
wiley +1 more source
Role of Salt Fingering in Recovering the Arabian Sea Oxygen Minimum Zone
Abstract Dissolved oxygen (DO) is vital for structuring marine ecosystems and biogeochemistry, making it a sensible indicator of oceanic health. The DO concentration varies spatially, and there are several regional ocean basins characterized by low subsurface oxygen levels.
Abhijit Shee, Bishakhdatta Gayen
wiley +1 more source
Abstract Vertical heat exchange within the upper ocean critically influences regional climate but remains difficult to observe directly. In the Gulf of Mexico, the Loop Current and its associated eddies significantly enhance this exchange. High‐resolution glider observations reveal that this transport is dominated by sub‐daily variability an order of ...
Sakib Mahmud +4 more
wiley +1 more source
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr +19 more
wiley +1 more source

