Results 11 to 20 of about 2,205 (65)
Virus-Mediated Self-Assembly of Functional Cyclodextrins for Antiviral Inhibition. [PDF]
A sialic acid (SA)‐functionalized cyclodextrin (CD) self‐assembles on SARS‐CoV‐2 through ligand–receptor recognition, nucleating cooperative supramolecular polymer growth that blocks infection. The adaptive assembly requires both ligand binding and host–guest polymerization, remains active across variants, and can be tuned by coassembly, establishing ...
Hernando PJ +10 more
europepmc +3 more sources
Shewanella oneidensis and Bacillus subtilis, both harboring prophages, reveal a novel biosynthetic route to scalable and programmable DNA superstructures in flower‐ and wire‐like shapes, respectively. Activation of prophages is achieved via 3‐hour starvation and monitored using reporter strains.
Gabriel Antonio S. Minero +7 more
wiley +2 more sources
Abstract Objective This study reports maternal outcomes in women with risk factors for placenta accreta spectrum disorder (PAS) with cesarean section on the scheduled date and before in a setting where the intention was to wait at least until 36 weeks of gestation.
Lisanne R. Bonsen +4 more
wiley +1 more source
Multiscale numerical sensitivity simulations of a mesoscale gravity‐wave event
High‐resolution WRF simulations of the February 14–15, 1992 STORM‐FEST event show that mesoscale gravity‐wave genesis occurs via geostrophic adjustment within an upper‐level unbalanced jet, while wave ducting governs maintenance. High‐resolution (1 km), improved physical parameterization, and targeted sensitivity simulations demonstrate that upstream ...
Rajan Bhandari +2 more
wiley +1 more source
ABSTRACT Sepsis is a life‐threatening condition characterized by dysregulated systemic inflammation and high mortality rates. Mesenchymal stem/stromal cells (MSCs) have emerged as promising immunomodulatory agents; however, genetic engineering strategies can enhance their therapeutic efficacy.
Alana Costa de Oliveira +7 more
wiley +1 more source
Establishing a Biophotonic Signature of Brain Ageing
If we excite autofluorescence from brains with a 488 nm laser, young brain autofluorescence shows blue‐shifted spectra; aged brain autofluorescence shows red‐shifted spectra. This spectral shift is predicted by plasma SM32:2 levels. These signals allow unbiased distinction of an ageing from a young brain.
Mary Slayo +6 more
wiley +1 more source
“Hold on, I'm comin'”: Copyright, political campaigns, and the limits of songwriter control
Abstract This article examines how songwriters in the United States object to the unwanted performance of their musical works at live political events, and the legal options available to challenge such uses. Prompted by the repeated use of ‘Hold On, I'm Comin'’ as outro music at Donald Trump's campaign events between 2020 and 2024, and the recent ...
Joel Cooper, Marie Hadley
wiley +1 more source
Epimer discrimination remains challenging due to subtle NMR differences. Here, we propose a methodology based on 13C‐RCSA and RDC anisotropic parameters, enabling the assignment of two flexible tetraprenyltoluquinol epimers (1a and 1b) with remote stereoclusters.
Juan Carlos C. Fuentes‐Monteverde +6 more
wiley +2 more sources
ApoE lipidation state directs immunometabolic reprogramming of human microglia
Abstract INTRODUCTION ApoE ε4 is the strongest genetic risk factor for Alzheimer's disease (AD). Emerging evidence suggests that ApoE4 increases AD risk by disrupting microglial metabolism and function. However, whether ApoE lipidation state contributes to microglial dysfunction remains poorly understood. METHODS Human microglia were treated with lipid‐
Tsion G. Shiferaw +14 more
wiley +1 more source
The Genomic Landscape of Metallic Colour Variation in Ground Beetles
ABSTRACT The metallic colour variation of beetles is a spectacular feature that has inspired diverse human cultures. However, little is known about the genetic basis of this trait or its ecological importance. In this study, we characterize the geographical distribution, optical mechanism, genetic basis and ecological and evolutionary importance of ...
Yi‐Ming Weng +5 more
wiley +1 more source

