Results 101 to 110 of about 125,560 (309)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The monetary policy consequences of enlargement [PDF]
Europäische Wirtschafts- und Währungsunion, EU-Erweiterung, Geldpolitik, European Economic and Monetary Union, EU enlargement, Monetary ...
Carsten Hefeker
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Migration and Labour Mobility in an Enlarged European Union [PDF]
How many will come? Thousands, millions? Does Europe need a New Iron Cuitain? These questions dominate the origoing negotiations of the East Enlargements of the European Union (EU) Western Europeans are afraid of being overflowed by cheap(er) eastern ...
T. Straubhaar
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Enlargement and the EU Periphery: The Impact of Changing Market Potential [PDF]
We study the impact of changing relative market access in an enlarged EU on the economies of incumbent Objective 1 regions. First, we track the impact of external opening on internal spatial configurations in a three-region economic geography model ...
Marius Brülhart +2 more
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Are EU-15 and CEEC agricultural exports in competition? Evidence for 1995-2005 [PDF]
This paper analyses the extent of agricultural competition between EU-15 countries and CEECs during the period 1995–2005 in the light of future EU membership. Finger and Kreinin's index is computed with the BACI database provided by CEPII.
Julie Le Gallo, Marie-Line Duboz
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Extreme Coexceedances in New EU Member States' Stock Markets [PDF]
We analyze the financial integration of the new European Union (EU) member states' stock markets using the negative (positive) coexceedance variable that counts the number of large negative (large positive) returns on a given day across the countries. We
Angelo Ranaldo, Charlotte Christiansen
core