The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Efficacy of the feed additive consisting of <i>Clostridium butyricum</i>FERM BP-2789 (Miya-Gold®) for chickens for fattening, chickens reared for laying and minor poultry species (excluding laying birds) Miyarisan Pharmaceutical Co. Ltd. [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +18 more
europepmc +1 more source
The paper’s main objective is to investigate the empirical link between the fiscal balance and the current account (i.e. the twin deficits phenomenon).
Aristovnik, Aleksander, Djurić, Sandra
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Bridging the gap between economic regulation and the right to health: a study on renewable energy, financial inclusion, and under-5 mortality in EU administrative contexts. [PDF]
Ning X, Arshad R.
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Safety and efficacy of a feed additive consisting of riboflavin 80% (vitamin B<sub>2</sub>) produced with <i>Saccharomyces cerevisiae</i>ATCC SD-8628 for all animal species (Amyris Inc). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Characterizing the Compound Extreme Temperature and PM<sub>2.5</sub> Pollution Events: A Multi-Country Analysis. [PDF]
Chen D, Zahid M, Qiu M.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source

