Results 91 to 100 of about 1,143,945 (288)

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

open access: yesAdvanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia   +4 more
wiley   +1 more source

Urban Geography Compression Patterns: Non-Euclidean and Fractal Viewpoints

open access: yesAppliedMath
The intersection of fractals, non-Euclidean geometry, spatial autocorrelation, and urban structure offers valuable theoretical and practical application insights, which echoes the overarching goal of this paper.
Daniel A. Griffith   +1 more
doaj   +1 more source

System of Axioms of Euclidean Geometry [PDF]

open access: yes
In this paper, we define Euclidean geometry and prove the existence theorem of Euclidean geometry by using the axiomatic method. Thereby we give the system of Axioms of Euclidean Geometry and prove its consistency.
1722   +5 more
core  

International Journal of Mathematical Combinatorics, Vol.7A [PDF]

open access: yes, 2013
The International J.Mathematical Combinatorics (ISSN 1937-1055) is a fully refereed international journal, sponsored by the MADIS of Chinese Academy of Sciences and published in USA quarterly comprising 460 pages approx.
Mao, Linfan (Editor-in-Chief)
core   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

open access: yesAdvanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa   +6 more
wiley   +1 more source

An exact five dimensional Weyl-geometry Gauss-Bonnet black hole

open access: yesPhysics Letters B
We present a new exact black hole solution of a 5-dimensional Weyl-geometry Gauss-Bonnet theory of gravity. The Euclidean sector defines a fully regular metric coupled to the Weyl vector field.
Sebastian Bahamonde, Máximo Bañados
doaj   +1 more source

Non-Euclidean geometry for secondary schools

open access: yes, 2014
The aim is appropriate elaboration of the subject non-Euclidean geometry to high school. The work includes historical introduction that de- scribes the path to the discovery of non-Euclidean geometry.
Miháliková, Lucia
core  

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

open access: yesAdvanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami   +7 more
wiley   +1 more source

Topics in Non-Euclidean geometry [PDF]

open access: yes, 1959
Thesis (M.A.)-- University of Wichita, College of Liberal Arts and Sciences, Dept. of MathematicsIt is difficult for a high school student to fully appreciate the study of Euclidean geometry without some notion of its relation to other geometries and ...
Carter, Martin
core   +2 more sources

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

open access: yesAdvanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu   +7 more
wiley   +1 more source

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