Results 101 to 110 of about 1,438,246 (328)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Non-Euclidean Geometry, Nontrivial Topology and Quantum Vacuum Effects

Universe, 2018
Space out of a topological defect of the Abrikosov–Nielsen–Olesen (ANO) vortex type is locally flat but non-Euclidean. If a spinor field is quantized in such a space, then a variety of quantum effects are induced in the vacuum.
Yurii A. Sitenko, Volodymyr M. Gorkavenko   +1 more
doaj   +1 more source

Interpretations of Euclidean Geometry [PDF]

Transactions of the American Mathematical Society, 1990
Following Tarski, we view n n -dimensional Euclidean geometry as a first-order theory E n {E_n} with an infinite set of axioms about the relations of betweenness (among points on a line) and equidistance (among pairs of points). We show that for k > n
openaire   +1 more source

Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D

Advanced Science, EarlyView.
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley   +1 more source

Reconstructing Coherent Functional Landscape From Multi‐Modal Multi‐Slice Spatial Transcriptomics by a Variational Spatial Gaussian Process

Advanced Science, EarlyView.
This study introduces stVGP, a variational spatial Gaussian process framework for multi‐modal, multi‐slice spatial transcriptomics. By integrating histological and genomic data through hybrid alignment and attention‐based fusion, stVGP reconstructs coherent 3D functional landscapes.
Zedong Wang, Bowen Fu, Chuanchao Zhang, Xiaoping Liu   +3 more
wiley   +1 more source

Artistic Demonstrations by Euclidean Geometry: Possible in 2D but Impossible in 3D [PDF]

, 2017
Abraham Tamir
openalex   +1 more source

Accelerated Discovery of Topological Conductors for Nanoscale Interconnects

Advanced Science, EarlyView.
Copper interconnects exhibit a sharp increase in resistivity at ultra‐scaled dimensions, threatening continued miniaturization of integrated circuits. The gapless surface states of topological semimetals provide conduction channels resistant to localization.
Alexander C. Tyner, William Rogers, Po‐Hsin Shih, Yi‐Hsin Tu, Gengchiau Liang, Hsin Lin, Ching‐Tzu Chen, James M. Rondinelli   +7 more
wiley   +1 more source

Urban Geography Compression Patterns: Non-Euclidean and Fractal Viewpoints

AppliedMath
The intersection of fractals, non-Euclidean geometry, spatial autocorrelation, and urban structure offers valuable theoretical and practical application insights, which echoes the overarching goal of this paper.
Daniel A. Griffith, Sandra Lach Arlinghaus   +1 more
doaj   +1 more source

Customizing Tactile Sensors via Machine Learning‐Driven Inverse Design

Advanced Science, EarlyView.
ABSTRACT Replicating the sophisticated sense of touch in artificial systems requires tactile sensors with precisely tailored properties. However, manually navigating the complex microstructure‐property relationship results in inefficient and suboptimal designs.
Baocheng Wang, Depeng Kong, Zhiao He, Jikai Liang, Yuyao Lu, Zikang Deng, Honghe Li, Mengke Wang, M. Jamal Deen, Zhiqiu Ye, Shuyao Zhou, Huayong Yang, Honghao Lyu, Jun Chen, Kaichen Xu, Geng Yang   +15 more
wiley   +1 more source

Geometry and Astronomy: Pre-Einstein Speculations of Non-Euclidean Space [PDF]

, 2012
Helge Kragh
openalex   +1 more source