Results 121 to 130 of about 93,156 (306)

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen   +6 more
wiley   +1 more source

Kinematic Mapping in Semi-Euclidean 4-Space

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014
We study the some algebraic properties of matrix associated to Hamilton operators is defined for semi-quaternions. The kinematic mapping corresponding to these operators in semi-Euclidean 4-space is same as the kinematic mapping of Blaschke and Grünwald ...
Mehdi JAFARI
doaj  

3D Reconstruction with Uncalibrated Cameras Using the Six-Line Conic Variety

open access: yes, 2008
We present new algorithms for the recovery of the Euclidean structure from a projective calibration of a set of cameras with square pixels but otherwise arbitrarily varying intrinsic and extrinsic parameters.
Carballeira, Pablo   +6 more
core   +1 more source

A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces

open access: yesAdvanced Science, EarlyView.
A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren   +5 more
wiley   +1 more source

Euclidean space dyon solutions

open access: yes, 2005
157-166Using a Cabbibo-Ferrari type non-Abelian field tensor, dyon solutions have been obtained in temporal gauge. Defining the Euclidean fields and imposing the conditions of self and anti-self duality, the obtained solutions have been shown to be ...
Singh, Vinod, Tripathi, B V, Joshi, D C
core  

Realizing Finite Groups in Euclidean Space

open access: yes, 2000
A set of points W in Euclidean space is said to realize the finite group G if the isometry group of W is isomorphic to G.
Albertson, Michael O, Boutin, Debra L
core   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin   +11 more
wiley   +1 more source

Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction

open access: yesAdvanced Science, EarlyView.
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen   +3 more
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

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