Results 211 to 220 of about 119,956 (261)

Tip60‐Mediated USP22 Lactylation Drives Glutamine Metabolic Reprogramming via SLC25A5 in TNBC

Advanced Science, EarlyView.
Tip60‐mediated USP22 K134 lactylation, stabilizing SLC25A5 to enhance glutamine metabolism and α‐KG secretion. The secreted α‐KG drives GPR91‐dependent M2 macrophage polarization, promoting triple‐negative breast cancer progression. Targeting this axis synergizes with CB‐839, offering a promising therapeutic strategy for TNBC.
Fang Zhen, Hongyi Wang, Ningzhi Zhang, Le Wang, Huiyuan Tian, Luxi Kang, Zhanpeng Liu, Jing Hu   +7 more
wiley   +1 more source

eIF3e-mediated translational checkpoint maintains immune tolerance and prevents lymphoid malignancy. [PDF]

J Exp Med
Lin L, Chen P, Wang J, Huang C, Lin X, Liu C, Liao K, Wu J, Chadburn A, Zhang Y, Song H, Wang C, Wan Z, Zhao J, Cao G, Wang X, Yang L, Yao N, Hong Y, Xiao Z, Wolf DA, Liu WH, Xiao C.   +22 more
europepmc   +1 more source

The Interplay Between Molybdopterin Synthase and Metal Metabolism Contributes to Pathogenicity in Acinetobacter baumannii

Advanced Science, EarlyView.
Pathogenic Acinetobacter baumannii scavenges metal ions as nutritional elements to survive within the host. This study demonstrates that molybdopterin synthase is essential for pathogenesis and full virulence during infection. Molybdopterin synthase subunit MoaE constitutes an intrinsically disordered C‐terminal histidine rich tail, which mediates ...
Min Jiao, Wenbo He, Zhenlin Ouyang, Ruochen Wang, Jiaxin Zhang, Xin Liu, Yiting Jing, Qinyue Yu, Xiaoyu He, Qian Qin, Litao Guo, Peter M. Hwang, Fang Zheng, Yurong Wen   +13 more
wiley   +1 more source

Liquid‑liquid phase separation and post‑transcriptional regulation intersection: A new paradigm of RNA‑binding protein condensates in hepatocellular carcinoma malignant phenotypes (Review). [PDF]

Mol Med Rep
Liu X, Huang Y.
europepmc   +1 more source

The integrated stress response kinase GCN2 prevents ZAKα-Dependent inflammatory hyperactivation in macrophages. [PDF]

J Biol Chem
Requião RD, Lima-Silva LF, Estevão P, Costa WLG, Zani NC, Vasconcelos IC, Silva ÍEP, Xu TT, Prado HMDA, Steigenberger B, Bengtson MH, Murray PJ, Moraes-Vieira PM.   +12 more
europepmc   +1 more source

PABPC1 in Cancer: From a Translational Housekeeper to a Stress-Responsive Regulatory Hub. [PDF]

Cancer Sci
Zhang C, Zhu Y, Long W.
europepmc   +1 more source

Mitophagy coordinates organelle crosstalk in health and diseases. [PDF]

Signal Transduct Target Ther
Wu M, He P, Lian Y, Zhang T, Wu Y, Wang L, Tang D, Yao Y, Yao R.   +8 more
europepmc   +1 more source

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis <i>in vitro</i> and <i>in vivo</i>. [PDF]

Int J Mol Med
Liang Y, Chen J, Li H, Xiong J, You J, Wang L, Wu J, Zheng Y, Luo M.   +8 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Isolation of Eukaryotic Initiation Factor 2 from Rat Brain

Journal of Neurochemistry, 1985
Abstract: Eukaryotic initiation factor 2 (eIF‐2) was isolated from salt‐washed microsomes of 4‐day‐old rat brain which show a high rate of protein synthesis. A three‐step purification scheme was employed, including heparin‐Sepharose, phosphocellulose, and DEAE‐cellulose column chromatography.
C, Calés, M, Salinas, J L, Fando
openaire   +2 more sources

Roles of Eukaryotic Initiation Factor 2 and Eukaryotic Initiation Factor 2 Ancillary Protein Factors in Eukaryotic Protein Synthesis Initiation

1987
The available evidence indicates that although the basic steps of peptide chain initiation are similar in all eukaryotic cells, the specific regulatory mechanisms may be different in animal cells and in lower eukaryotic cells. The basic steps are: (1) formation of a ternary complex between eukaryotic peptide chain initiation factor 2 (eIF-2), Met ...
Naba K. Gupta, Mir F. Ahmad, Debopam Chakrabarti, Nargis Nasrin   +3 more
openaire   +1 more source