Results 251 to 260 of about 27,996,561 (298)

Mitochondria-sarcoplasmic reticulum crosstalk as a modulator of skeletal muscle mass. [PDF]

J Physiol Biochem
Casuso RA.
europepmc   +1 more source

Androgen receptor drives lenvatinib resistance in hepatocellular carcinoma through transcriptional activation of EIF3I and a downstream ceRNA axis. [PDF]

Oncol Lett
Liu C, Zhang B, Jin Y, Chen Z, Wang M, Wu Z.   +5 more
europepmc   +1 more source

Sparsomycin inhibits translation through a conserved mechanism across all domains of life. [PDF]

Nucleic Acids Res
Paranjpe MN, Leroy EC, Syroegin EA, Flemmich L, Thaler J, Gillard M, Bougas A, Kournoutou G, Dinos GP, Renault TT, Micura R, Innis CA, Polikanov YS.   +12 more
europepmc   +1 more source

Structural studies of nedicistrovirus IRES-driven, initiation factor-independent translation shed light on key steps of eukaryotic translation elongation. [PDF]

Nucleic Acids Res
De S, Altomare CG, Abaeva IS, Dadhwal P, Garg P, Acosta-Reyes F, Brown ZP, Pestova TV, Hellen CUT, Frank J.   +9 more
europepmc   +1 more source

The African Swine Fever Virus Early Transcription Factor Complex Reveals a Prototype for Nucleocytoplasmic Large DNA Viruses

Werner F, Cackett G, Dulson C, Sýkora M, Pilotto S, Roberts A, Gouge J.   +6 more
europepmc   +1 more source

Regulation of eukaryotic initiation factor-2 expression during sepsis

American Journal of Physiology-Endocrinology and Metabolism, 1994
Protein synthesis is stimulated at the level of peptide chain initiation in livers from rats with a sterile or septic abscess. In contrast, peptide chain initiation is inhibited in fast-twitch skeletal muscles from septic rats. We investigated the possible mechanisms responsible for these differential changes in peptide chain initiation between liver ...
T C, Vary, C V, Jurasinski, A M, Karinch, S R, Kimball   +3 more
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Isolation of Eukaryotic Initiation Factor 2 from Rat Brain

Journal of Neurochemistry, 1985
Abstract: Eukaryotic initiation factor 2 (eIF‐2) was isolated from salt‐washed microsomes of 4‐day‐old rat brain which show a high rate of protein synthesis. A three‐step purification scheme was employed, including heparin‐Sepharose, phosphocellulose, and DEAE‐cellulose column chromatography.
C, Calés, M, Salinas, J L, Fando
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Roles of Eukaryotic Initiation Factor 2 and Eukaryotic Initiation Factor 2 Ancillary Protein Factors in Eukaryotic Protein Synthesis Initiation

1987
The available evidence indicates that although the basic steps of peptide chain initiation are similar in all eukaryotic cells, the specific regulatory mechanisms may be different in animal cells and in lower eukaryotic cells. The basic steps are: (1) formation of a ternary complex between eukaryotic peptide chain initiation factor 2 (eIF-2), Met ...
Naba K. Gupta, Mir F. Ahmad, Debopam Chakrabarti, Nargis Nasrin   +3 more
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The Role of Phosphorylation in the Regulation of Eukaryotic Initiation Factor 2 Activity

1982
Publisher Summary The regulation of protein synthesis by changes in the rate of translational initiation is a rapid, short-term mechanism for modifying gene expression in animal cells. Prominent examples include viral inhibition of host protein synthesis, the expression of latent mRNA during embryonic development, the coordination of ribosome and ...
R, Jagus, D, Crouch, A, Konieczny, B, Safer   +3 more
openaire   +2 more sources