Results 231 to 240 of about 6,793 (328)

A survey of downstream applications of evolutionary scale modeling protein language models

open access: yesQuantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The evolutionary scale modeling (ESM) series is promising to revolutionize protein science and engineering through large language models (LLMs), providing a robust framework for understanding the relationships among sequences, structures, and functions of proteins.
Qingyu Yang, Jiale Yu, Jie Zheng
wiley   +1 more source

Mechanistic two‐pathway modeling of substrate inhibition in lactic acid bacteria for enhanced fermentation control

open access: yesQuantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Substrate inhibition in lactic acid bacteria (LAB) fermentation occurs when substrate concentration exceeds a critical value, leading to reduced cell growth and thus inefficient lactic acid production. Many efforts, including experimental and kinetic models, have been devoted to elucidate the possible mechanisms of substrate inhibition ...
Guoxi Zheng, Junwen Mao
wiley   +1 more source

Optimal energy management of water networks under quality conditions

open access: yesInternational Transactions in Operational Research, Volume 33, Issue 2, Page 926-951, March 2026.
Abstract In the context of sustainability, which has become fundamental today, we aim to optimize (reduce) the energy consumption due to the use of pumps that bring water from all the different reservoirs to the nodes of the distribution network. The proposed model allows us, thanks to the use of smart meters and new 5G technologies, to determine the ...
Gabriella Colajanni   +2 more
wiley   +1 more source

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