Results 21 to 30 of about 2,223 (217)

Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma.

PLoS Neglected Tropical Diseases, 2022
Eumycetoma is a chronic subcutaneous neglected tropical disease that can be caused by more than 40 different fungal causative agents. The most common causative agents produce black grains and belong to the fungal orders Sordariales and Pleosporales.
Wilson Lim, Bertrand Nyuykonge, Kimberly Eadie, Mickey Konings, Juli Smeets, Ahmed Fahal, Alexandro Bonifaz, Matthew Todd, Benjamin Perry, Kirandeep Samby, Jeremy Burrows, Annelies Verbon, Wendy van de Sande   +12 more
doaj   +2 more sources

Canine eumycetoma caused by Madurella pseudomycetomatis

Medical Mycology Case Reports, 2022
Canine eumycetoma is a rare granulomatous disease caused by dematiaceous fungi. A 2-year-old Great Dane dog had a subcutaneous mass in the right thigh that was surgically removed. Grossly, numerous black-grains were visible. Histologically subcutaneous pyogranulomas were centered on myriads of pigmented fungal elements.
Francesco Albanese, Luisa Vera Muscatello, Alice Michelutti, Christian Falcaro, Laura Bellentani, Patrizia Danesi   +5 more
openalex   +4 more sources

A Case of Trauma-Induced Falciformispora lignatilis Eumycetoma in a Renal Transplant Recipient [PDF]

Tropical Medicine and Infectious Disease, 2021
Mycetoma is a chronic, granulomatous, subcutaneous infection caused by several species of fungi and soil-inhabiting bacteria, and is divided into eumycetoma and actinomycetoma, respectively. Endemicity is described with worldwide distribution within the “
Maxwell Olenski, Catriona Halliday, James Gullifer, Elena Martinez, Amy Crowe, Harsha Sheorey, Jonathan Darby   +6 more
doaj   +2 more sources

A Rare Case of Oral Cavity Eumycetoma

Annals of Maxillofacial Surgery, 2023
Abstract Rationale: Mycetoma is a chronic granulomatous infection that involves the skin and subcutaneous tissue which presents as an abscess with multiple draining sinuses. It is common in the tropical and subtropical regions where the conditions favour the growth of the soil saprophytes – fungi and bacteria.
Kavita Wadde, Samir Dashrath Khaire, Tabita Joy, Manisha Ahire Sardar, Mrimingsi Kri, Lakshmi Venkatakrishnan   +5 more
openalex   +3 more sources

White Grain Eumycetoma due to Aspergillus flavus in Infancy: A Rare Case Report from Assam

Journal of Pure and Applied Microbiology, 2017
Mycetoma is a slowly progressive, chronic granulomatous infection of skin and subcutaneous tissue caused by traumatic inoculation of either fungi (eumycotic) or bacteria (actinomycotic).
Lakshyasri Baishya, Madhab Kalita, Ajanta Sharma, Bornali Sarma Dutta, Debeeka Hazarika   +4 more
doaj   +2 more sources

Eumycetoma: A Perspective for Military Primary Care [PDF]

Military Medicine, 2021
ABSTRACT This is a case report of a 42-year-old woman who presented to a clinic with a history of progressive left foot and ankle swelling. She had a suspected history of myectoma, but had never been officially diagnosed despite repeated cultures and debridements over the course of decades.
Joshua Tunnage, Jonathan Vignali, Christa Eickhoff   +2 more
openalex   +4 more sources

Eumycetoma caused by Alternaria alternata in an immunocompetent host: A rare case report

Clinical Dermatology Review, 2020
Mycetoma is a chronic granulomatous subcutaneous infection caused by either true fungi (eumycetoma) or filamentous anaerobic bacteria (actinomycetoma). Herein, we report a case of mycetoma foot due to a rare opportunistic fungus in a male farmer.
Vasudha A Belgaumkar, Ravindranath Brahmadeo Chavan, Vijay Vidyadhar Raut, Pallavi Prataprao Patil   +3 more
doaj   +2 more sources

Carcinoma Cuniculatum Masquerading as Eumycetoma: An Unacquainted Entity Posing a Diagnostic Dilemma [PDF]

Türk Patoloji Dergisi
Carcinoma cuniculatum (CC) is a rare and distinct clinicopathological variant of well-differentiated squamous cell carcinoma. It is a rare and slow-growing tumor with a peculiar infiltrative growth pattern resembling rabbit burrows (cuniculi). It usually
Pooja SHARMA, Pragya JAIN, Ankur GARG, Sonal SHARMA   +3 more
doaj   +2 more sources

Eumycetoma causative agents: A systematic review to inform the World Health Organization priority list of fungal pathogens. [PDF]

Med Mycol
The World Health Organization, in response to the growing burden of fungal disease, established a process to develop a fungal priority pathogens list. This systematic review aimed to evaluate the epidemiology and impact of eumycetoma.
Clark JE, Kim HY, van de Sande WWJ, McMullan B, Verweij P, Alastruey-Izquierdo A, Chakrabarti A, Harrison TS, Bongomin F, Hay RJ, Oladele R, Heim J, Beyer P, Galas M, Siswanto S, Dagne DA, Roitberg F, Gigante V, Beardsley J, Sati H, Alffenaar JW, Morrissey CO.   +21 more
europepmc   +4 more sources

Madurella mycetomatis, the main causative agent of eumycetoma, is highly susceptible to olorofim [PDF]

, 2020
OBJECTIVES: Eumycetoma is currently treated with a combination of itraconazole therapy and surgery, with limited success. Recently, olorofim, the lead candidate of the orotomides, a novel class of antifungal agents, entered a Phase II trial for the ...
Birch, M. (Mike), Eadie, K. (Kimberley), Fahal, A.H. (Ahmed), Konings, M. (Mickey), Lim, W. (Wilson), Oliver, J.D. (Jason D.), Rijnders, B.J.A. (Bart), Sande, W.W.J. (Wendy) van de, Verbon, A. (Annelies)   +8 more
core   +3 more sources