Results 21 to 30 of about 2,743 (217)

A drug-repurposing screen of FDA- and EMA-approved drugs identifies two NF-κB inhibitors active against eumycetoma. [PDF]

J Antimicrob Chemother
Background Mycetoma caused by Madurella mycetomatis (eumycetoma) is a neglected tropical disease that forms tumorous lesions in the subcutaneous tissue. The current standard treatment for eumycetoma consists of antifungal treatment combined with surgery,
Ma J, van Doodewaerd BR, Biersack B, Verbon A, Geurink PP, van de Sande WWJ.   +5 more
europepmc   +2 more sources

Concurrent chromoblastomycosis and eumycetoma: a unique case of dual neglected tropical fungal diseases in Asia. [PDF]

PLoS Negl Trop Dis
Chromoblastomycosis (CBM) and mycetoma, as implantation mycoses, have been listed as neglected tropical diseases (NTDs) by the World Health Organization. The concurrent occurrence of these two NTDs in a single patient is extremely rare.
Liu W, Xie S, Zhu G, Qin S, Li M, Yin S, Lai W, Lu C, Chen Q, Feng P.   +9 more
europepmc   +2 more sources

Diagnosis and Management of a Long-Standing Eumycetoma of the Wrist in Somalia: A Case Report in a Resource-Limited Setting [PDF]

International Medical Case Reports Journal
Adam Abdulahi Mohamed,1,2 Shafie Abdulkadir Hassan,3 Mhmoud Mohmed Mhmoud Hassan1 1Center for Mycetoma Research, Mogadishu, Somalia; 2Faculty of Health Sciences, Central University of Science and Technology, Baladweyn, Hiiran, Somalia; 3Faculty of ...
Mohamed AA, Hassan SA, Hassan MMM
doaj   +2 more sources

Mycetoma Epidemiology and Clinical Findings in Mogadishu, Somalia. [PDF]

J Trop Med
Background: Mycetoma is a public health problem with a high prevalence in Africa. Materials and Methods: The study included 50 cases presenting at a tertiary care research hospital, retrospectively (cases we visited and followed up between November 2022 and March 2023) and prospectively between 1 August and 30 September 2024.
Doğan A, Adan FN, Ali TA, Çelik AK, Ali AM.   +4 more
europepmc   +2 more sources

Simultaneous Detection of Four Madurella Species Using Loop-Mediated Isothermal Amplification (LAMP) for Eumycetoma Diagnosis. [PDF]

Mycopathologia
Eumycetoma is a neglected tropical disease caused primarily by a Madurella mycetomatis infection, besides other related species. In this study, we designed a novel loop-mediated isothermal amplification (LAMP) primer set capable of simultaneously ...
Yoshioka I, Fahal AH, Sow D, Kaneko S, Mori Y, Ban S, Yaguchi T.   +6 more
europepmc   +2 more sources

Sandalwood Sesquiterpene (Z)-α-Santalol Exhibits In Vivo Efficacy Against Madurella mycetomatis in Galleria mellonella Larvae [PDF]

Molecules
In continuation of our recent report on the in vitro activity of sandalwood essential oils and their major components, the sesquiterpenes (Z)-α- and -β-santalols, against the pathogenic fungus Madurella mycetomatis, causative agent of the neglected ...
Shereen O. Abd Algaffar, Stephan Seegers, Shaoqin Zhou, Prabodh Satyal, William N. Setzer, Thomas J. Schmidt, Sami A. Khalid   +6 more
doaj   +2 more sources

Two simultaneous mycetomas caused by Fusarium verticillioides and Madurella mycetomatis [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2017
Mycetoma is a chronic granulomatous disease, classified into eumycetoma caused by fungi and actinomycetoma due to aerobic filamentous actinomycetes. Mycetoma can be found in geographic areas near the Tropic of Cancer.
Alexandro Bonifaz, Mariana Saldaña, Javier Araiza, Patricia Mercadillo, Andrés Tirado-Sánchez   +4 more
doaj   +4 more sources

Fusarium subglutinans: A new eumycetoma agent

Medical Mycology Case Reports, 2013
Eumycetoma is a chronic subcutaneous mycosis mainly caused by Madurella spp. Fusarium opportunistic infections in humans are often caused by Fusarium solani and Fusarium oxysporum. We report a case of eumycetoma by F. subglutinans, diagnosed by clinical aspect and culture, and confirmed by PCR sequencing.
Campos-Macías, Pablo, Arenas-Guzmán, Roberto, Hernández-Hernández, Francisca   +2 more
exaly   +3 more sources

Eumycetoma causative agents: A systematic review to inform the World Health Organization priority list of fungal pathogens [PDF]

Medical Mycology
The World Health Organization, in response to the growing burden of fungal disease, established a process to develop a fungal priority pathogens list. This systematic review aimed to evaluate the epidemiology and impact of eumycetoma.
Julia E. Clark, H. Y. Kim, W. V. D. van de Sande, Brendan McMullan, P. Verweij, A. Alastruey-Izquierdo, Arunaloke Chakrabarti, Thomas S Harrison, F. Bongomin, Roderick J Hay, R. Oladele, Jutta Heim, P. Beyer, Marcelo Galas, Siswanto Siswanto, D. Dagne, Felipe Roitberg, Valeria Gigante, J. Beardsley, Hatim Sati, Jan-Willem C. Alffenaar, C. O. Morrissey   +21 more
semanticscholar   +4 more sources

Environmental detection of eumycetoma pathogens using multiplex real-time PCR for soil DNA in Sennar State, Sudan [PDF]

Tropical Medicine and Health, 2023
Background Mycetoma is a chronic disease affecting the skin and subcutaneous tissue endemic in the tropical and subtropical regions. Several bacteria and fungi can cause mycetoma, but fungal mycetoma (eumycetoma) is challenging because the treatment ...
Hiroki Hashizume, Suguru Taga, Masayuki K. Sakata, M. Hussein, E. Siddig, T. Minamoto, A. Fahal, Satoshi Kaneko   +7 more
semanticscholar   +5 more sources