Results 121 to 130 of about 2,365,633 (308)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Historical Studies on Central Europe, 2021 HSCE Historical Studies on Central Europe
doaj +2 more sources
Cultivating Europe: Democratic Europe - Social Europe - Educated Europe [PDF]
Proceedings of the Conference "Impact of Social Sciences and Humanities for a European Research Agenda - Valuation of SSH in mission-oriented research" VIENNA 2018, 2019 Katharina Berghöfer +6 more
openaire +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Science Europe Welcomes Efforts Towards European Open Science Cloud
, 2017 Science Europe welcomes the efforts made towards the European Open Science Cloud (EOSC). In this open letter, the Governing Board of Science Europe reinforces its view that research data should be permanently, publicly, and freely available for re-use ...
Science Europe
core +1 more source
Historical Studies on Central Europe, 2021 HSCE Historical Studies on Central Europe
doaj +2 more sources
Alter-Europe: Progressive Activists and Europe
, 2015 On 15 May 2011, ten days before the national general election, a crowd took over the Plaza del Sol in Madrid to protest against the lack of alternatives proposed by the two main parties, the centre-left Socialists and the right-wing ‘Popular Party’. Inspired by the recent events in Tahrir Square, one of their goals was to implement direct democracy in ...
openaire +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source