Results 101 to 110 of about 2,365,633 (308)

A Real-World Energy Management Dataset from a Smart Company Building for Optimization and Machine Learning

open access: yesScientific Data
We present a large real-world dataset obtained from monitoring a smart company facility over the course of six years, from 2018 to 2023. The dataset includes energy consumption data from various facility areas and components, energy production data from ...
Jens Engel   +11 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Europe Faces Europe

open access: yes, 2017
Europe Faces Europe examines Eastern European perspectives on European identity. The contributors to this volume map narratives of Europe rooted in Eastern Europe, examining their relationship to p ...
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Political journalism in transition: Western Europe in a comparative perspective

open access: yes, 2014
The 21st century has already seen dramatic changes affecting both journalism and politics. The rise of a range of new digital and networked communication technologies combined with the stagnation and decline of many traditional mass media has had a ...

core   +1 more source

Efta-barometer autumn 1992: Austria, Finland and Sweden

open access: yes, 1993
The survey was carried out simultaneously in the three EFTA-countries Austria, Finland, and Sweden. In each country approximately 1 000 persons were asked about their opinions about a unified Western Europe, and personal interest in European Community ...
Gallup Europe
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical challenges and patient experiences in early-onset colorectal cancer: insights from seven European countries

open access: yesBMC Gastroenterology
Background The incidence of early-onset colorectal cancer (eoCRC), defined as CRC diagnosed in individuals under 50, is rising globally. Younger patients often face diagnostic delays and receive care pathways designed for older populations.
Marianna Vitaloni   +6 more
doaj   +1 more source

Kin-state Engagement and Its Impact on Minority Protection: in Europe: Relevant Findings for Southeast Europe

open access: yes, 2023
Commissioned by the Council of Europe Office in Belgrade, this policy paper offers an overview of kin-state engagement in Europe, assessing its role in protecting targeted ethnic groups and outlining the most pressing challenges across Europe.
Udrea, Andreea   +2 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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