Results 81 to 90 of about 3,006,889 (310)

Myocardial infarction community registers: results of a WHO international collaborative study coordinated by the Regional Office for Europe

open access: yes, 1976
iii, 232 p.In 1965, the European governments asked the World Health Organization (WHO) to direct more of its activities to the field of cardiovascular diseases.
World Health Organization. Regional Office for Europe
core  

Highly reproducible and CMOS-compatible VO2-based oscillators for brain-inspired computing

open access: yesScientific Reports
With remarkable electrical and optical switching properties induced at low power and near room temperature (68 °C), vanadium dioxide (VO2) has sparked rising interest in unconventional computing among the phase-change materials research community.
Olivier Maher   +6 more
doaj   +1 more source

Enhancing foundation models for scientific discovery via multimodal knowledge graph representations

open access: yesWeb Semantics
Foundation Models (FMs) hold transformative potential to accelerate scientific discovery, yet reaching their full capacity in complex, highly multimodal domains such as genomics, drug discovery, and materials science requires a deeper consideration of ...
Vanessa Lopez   +8 more
doaj   +1 more source

Learning for the NHS on procurement and supply chain management: a rapid evidence assessment

open access: yesHealth Services and Delivery Research, 2014
Background: Procurement of clinical and non-clinical goods has been identified as one area for efficiency savings for the NHS. There is a need for robust evidence to help the NHS make informed decisions about how to make such savings and there is ...
Saba Hinrichs   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Health and the environment

open access: yes, 1977
iii, 161 p.This issue of “Public health in Europe” seeks to highlight some environmental health problems of current concern and to describe some of the activities of the World Health Organization Regional Office for Europe in this ...
World Health Organization. Regional Office for Europe
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Growing strings in a chemical reaction space for searching retrosynthesis pathways

open access: yesnpj Computational Materials
Machine learning algorithms have shown great accuracy in predicting chemical reaction outcomes and retrosyntheses. However, designing synthesis pathways remains challenging for existing machine learning models which are trained for single-step prediction.
Federico Zipoli   +4 more
doaj   +1 more source

Evidence on the links between patient experience and safety: a systematic review

open access: yesBMJ Open Quality
Background Patient experience and safety are central to healthcare quality, yet their relationship remains underexplored. While earlier evidence suggests a positive association, policy and practice are continually developing around the world. This review
Cara Witwicki   +7 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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