Results 61 to 70 of about 3,006,889 (310)

HIV/AIDS surveillance in Europe 2023: 2022 data

open access: yes, 2023
xxxi, 82 p.This report presents HIV/AIDS surveillance data for 2022, a year marked by increased population movements across Europe that have had an impact on HIV trends, particularly in European Union/European Economic Area ...
European Centre for Disease Prevention and Control   +1 more
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Eliminating bias: a routine commitment

open access: yesThe Lancet Regional Health. Europe, 2022
The Lancet Regional Health– Europe
doaj   +1 more source

The impact of the National Institute for Health Research Health Technology Assessment programme, 2003–13: a multimethod evaluation

open access: yesHealth Technology Assessment, 2015
Background: The National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme supports research tailored to the needs of NHS decision-makers, patients and clinicians. This study reviewed the impact of the programme, from 2003
Susan Guthrie   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Protecting the mental health of youth

open access: yesThe Lancet Regional Health. Europe, 2022
The Lancet Regional Health– Europe
doaj   +1 more source

Foundation models for materials discovery – current state and future directions

open access: yesnpj Computational Materials
Large language models, commonly known as LLMs, are showing promise in tacking some of the most complex tasks in AI. In this perspective, we review the wider field of foundation models—of which LLMs are a component—and their application to the field of ...
Edward O. Pyzer-Knapp   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Vaccinated and unvaccinated need to coexist with tolerance and respect

open access: yesThe Lancet Regional Health. Europe, 2022
The Lancet Regional Health – Europe
doaj   +1 more source

Collaborative artificial intelligence system for investigation of healthcare claims compliance

open access: yesScientific Reports
Healthcare fraud, waste and abuse are costly problems that have huge impact on society. Traditional approaches to identify non-compliant claims rely on auditing strategies requiring trained professionals, or on machine learning methods requiring labelled
Marco Luca Sbodio   +9 more
doaj   +1 more source

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