Results 51 to 60 of about 3,168,728 (312)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Building scientific excellence in Europe et Beyond [PDF]

open access: yes
Pour Science Europe, 2021 a été une année très importante : l’association fondée en 2011, a en une voix respectée et influente dans la politique de recherche européenne.
Science Europe
core  

A dressed singlet-triplet qubit in germanium

open access: yesNature Communications
In semiconductor hole spin qubits, low magnetic field (B) operation extends the coherence time ( $${T}_{2}^{*}$$ T 2 * ) but proportionally reduces the gate speed.
K. Tsoukalas   +17 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Statement of Intent on Open Research Europe [PDF]

open access: yes
La présente déclaration d’intention est signée par des organismes publics de financement de la recherche, des organisations de chercheurs et les ministères nationaux (ci-après dénommés « Signataires ») qui font partie du Groupe d’intérêt Open Research ...
Open Research Europe
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Health and the environment

open access: yes, 1977
iii, 161 p.This issue of “Public health in Europe” seeks to highlight some environmental health problems of current concern and to describe some of the activities of the World Health Organization Regional Office for Europe in this ...
World Health Organization. Regional Office for Europe
core  

Saplings of significance: Nurturing cultural value of new tree plantings through participatory opportunities

open access: yesPeople and Nature
Tree‐planting initiatives are a crucial part of international sustainability and climate action efforts. Yet, many of these initiatives fail to achieve their long‐term sustainability and climate goals.
Claire L. Narraway   +8 more
doaj   +1 more source

Quantitative prediction of mixture toxicity of AgNO3 and ZnO nanoparticles on Daphnia magna

open access: yesScience and Technology of Advanced Materials, 2020
Once metal-based engineered nanoparticles (NPs) are released into the aquatic environment, they are expected to interact with other existing co-contaminants. A knowledge gap exists as to how the interaction of NPs with other co-contaminants occurs.
Min Jeong Baek   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy