Results 31 to 40 of about 2,365,633 (308)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The idea of benefitting from the properties of III-V semiconductors and silicon on the same substrate has been occupying the minds of scientists for several years.
Katarzyna E. Hnida-Gut +3 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Europe to Keep Leading COVID-19 Pandemic and Crisis Recovery
Science Europe encourages EU Member States and Associated Countries to keep leading European and global projects to tackle the medical, social, and economic challenges brought on by COVID-19.
Science Europe
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Inferring experimental procedures from text-based representations of chemical reactions
The experimental execution of chemical reactions is a context-dependent and time-consuming process, often solved using the experience collected over multiple decades of laboratory work or searching similar, already executed, experimental protocols ...
Alain C. Vaucher +5 more
doaj +1 more source
The Wider Europe Matrix. CEPS Paperback. January 2004 [PDF]
This study is an attempt to think systematically about the enlarging European Union’s relationships with the rest of Europe and the arc of Arab and Muslim states that are Europe’s neighbours, from Morocco to Central Asia through Iraq – two vast regions ...
Emerson, Michael, Verheugen, Günter
core
The Revised Social Cohesion Strategy of the Council of Europe
Na summitu Vijeća Europe održanom 1997. godine kao jedan od prioritetnih ciljeva istaknuto je promicanje socijalne kohezije u europskim zemljama. Na tom je summitu utemeljen Odbor za socijalnu koheziju (CD - CS) kojem je određen zadatak izrade Strategije
Vijeće Europe,, Vijeće Europe
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

