Results 131 to 140 of about 6,679,772 (342)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Historical Studies on Central Europe, 2021 HSCE Historical Studies on Central Europe
doaj +2 more sources
Evaluation of Monilinia fructicola on apricot fruits [PDF]
, 2019 Monilinia fructicola has been a quarantine pathogen in Europe until 2014; however, the disease risk remains large for Prunus species, because of the continuing spreading around Europe.
Christen, D., Del Cueto, J., Stefani, P.
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Childbearing preferences and family issues in Europe: evidence from the Eurobarometer 2006 survey [PDF]
, 2007 Maria Testa
openalex +1 more source
A. Tovias, The European Communities\u27 Single Market: The Challenge of 1992 for Sub-Saharan Africa [PDF]
, 1990 Professor Tovias\u27 book is a refreshing and welcome addition to the existing literature on the different aspects of Europe 1992. The European Communities\u27 Single Market is divided into seven chapters.
Kwakwa, Edward
core +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Toward a consensus in the laboratory diagnostics of Fabry disease ‐ recommendations of a European expert group [PDF]
, 2011 Andreas Gal +2 more
openalex +1 more source
A New International Division of Labor in Europe: Offshoring and Outsourcing to Eastern Europe [PDF]
Europe is reorganizing its international value chain. I document these changes in Europe’s international organization of production with new survey data of Austrian and German firms investing in Eastern Europe. I show estimates of the share of intra-firm
Marin, Dalia
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source