Results 11 to 20 of about 2,046,421 (291)
AbstractAs the History of Science Society, which is based in America, holds its annual meeting in Utrecht, one of the key academic centers on the European continent, one may surmise that the field has returned home. Yet, this hardly reflects how today’s world of scholarship is constituted: in the historiography of science, “provincializing Europe” has ...
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Our current 1.1°C warmer world is already affecting natural and human systems in Europe (very high confidence1 ). Since AR5, there has been a substantial increase in detected or attributed impacts of climate change in Europe, including extreme events (high confidence).
Bednar-Friedl B.+49 more
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The Archaeogenetics of Europe [PDF]
A new timescale has recently been established for human mitochondrial DNA (mtDNA) lineages, making mtDNA at present the most informative genetic marker system for studying European prehistory. Here, we review the new chronology and compare mtDNA with Y-chromosome patterns, in order to summarize what we have learnt from archaeogenetics concerning five ...
Vincent Macaulay+8 more
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Coopératives, Europe : Cooperatives Europe [PDF]
Cooperatives Europe a ete creee le 1er mars 2005 pour conjuguer les forces cooperatives au niveau europeen, initiant un processus d’integration qui se poursuit en 2006. Gagner en visibilite pour faire entendre les specificites cooperatives aupres des institutions europeennes est un objectif important.
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Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta+3 more
wiley +1 more source
The idea of benefitting from the properties of III-V semiconductors and silicon on the same substrate has been occupying the minds of scientists for several years.
Katarzyna E. Hnida-Gut+3 more
doaj +1 more source
Living with systemic lupus erythematosus in 2020: a European patient survey
Objective The aim of this study was to analyse the 2020 burden of Systemic Lupus Erythematosus (SLE) in Europe, from the patients’ perspective.Methods In May 2020, Lupus Europe, the European umbrella patient association for SLE, designed and disseminated
Alain Cornet+3 more
doaj +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source