Results 21 to 30 of about 4,853,736 (241)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Organic in Europe: Prospects and Developments [PDF]
, 2018 In 2016/2017 the European organic food and farming sector continued to excel both in terms of organic production and market growth as well as the latest developments in European Union (EU) food and farming policy.
Busacca, Emanuele +3 more
core
Maturitas, 2017 The group of individuals aged 80 and over is growing faster than other segments of the population, and within this group the number of centenarians has risen exponentially worldwide. This paper reports the numbers of centenarians (total, and ratio relative to total population) in 32 European countries and their key characteristics: gender distribution,
Lia Araújo +4 more
openaire +5 more sources
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
The 'unseamed picture': conflicting narratives of women in the modern European past [PDF]
, 2008 This article arises from a personal journey through writing the history of women and gender in modern Europe. Other historians of Europe will no doubt recognise my experience of being pulled in different directions, between the general and the particular,
Abrams, L.
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Jules Romains’ vision of a united Europe in interwar France: legacy and ambiguities [PDF]
, 2013 The interwar period in Europe was characterised by a multi-faceted movement in favour of European integration. After the slaughter of the First World War, many intellectuals, writers, industrialists and politicians brought the idea of European unity to ...
Bogain, Ariane
core +1 more source
CREATIVITY STUDIES, 2009 How should Europe deal politically with its legacy as a so‐called “Christian civilization"? Should this imply an overt reference to God or to the Christian or Judeo‐Christian tradition in European constitutional documents (as was debated when the so‐called “Treaty Establishing a Constitution for Europe” was tabled)? This debate raised the old “politico‐
openaire +6 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source