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The Importance of Being Nice: An Institutionalist Analysis of French Preferences on the Future of Europe [PDF]
This article offers an institutionalist explanation of French preferences on the future of Europe from the Maastricht Treaty of 1992 through the Constitutional Treaty of 2004. It argues that the autonomous institutional logic of the constitution-drafting
Nicolas Jabko
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Croatian Accession to the European Union: Institutional Challenges [PDF]
Awareness of the need for environmental protection must in Croatia be translated into a clear, overall and long-term concept, particularly because of the process of rapprochement with the European Union (EU), in which it is one of the key topics.
Alida Ban, Katarina Ott
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Respect of the Article 8 of the European Convention for the Protection of Human Rights and Fundamental Freedoms in the recent case law of the European Court of Human Rights [PDF]
, 2020 Vojvodić Jovana D.
openalex +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
United Kingdom judges and European integration [PDF]
, 2015 The British, specifically the English, are widely regarded as awkward partners in the European project. Much of the criticism has come from anti-European integration politicians.
Birkinshaw, Patrick
core