Results 101 to 110 of about 76,141 (311)
"Influences on European Union Nuclear Waste Transport Policy" [PDF]
This paper identifies the evolution of pro- and anti-nuclear advocacy coalitions to their incorporation of the shipments issue in the late 1980's. The pro-nuclear waste transport advocacy coalition has come to include developed nuclear powers, such as ...
Anglim, Jennifer +2 more
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Governmental Positions on European Treaty Reforms: Towards a Dynamic Approach. [PDF]
Governmental positions are a powerful predictor of European treaty reforms. Yet, few empirical studies analyze the conditionalies between positions over different issues or conflict dimensions.
Finke, Daniel
core
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The European Free Trade Association – 50 Years of Existence [PDF]
The European Free Trade Association (EFTA) is an intergovernmental organization set up for the promotion of free trade and economic integration to the benefit of its four Member States: Iceland, Liechtenstein, Norway and Switzerland.
Trocan, Laura Magdalena
core
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Highlighting some of the challenges COVID-19 has posed to the European Convention on Human Rights. [PDF]
Sorinmade OA.
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Security and the Two-Level Game: The Treaty of Prüm, the EU and the Management of Threats. CEPS Working Documents No. 234, 1 January 2006 [PDF]
On 27 May 2005, seven Member States signed the Prüm Convention to step up cross-border cooperation, particularly in combating terrorism, cross-border crime and illegal migration.
Guild, Elspeth +3 more
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source

