Results 31 to 40 of about 44,566 (262)

Introducing good governance to local standards and regional democracy of the EU

Aspekti Publìčnogo Upravlìnnâ, 2020
It has been established that the implementation of good governance according to the standards of local and regional democracy of the EU is carried out in accordance with the Strategy for Innovation and Good Governance at Local Level, which provides for ...
Yurii Telychkan
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

SOME REFLECTIONS ON NORTH MACEDONIA’S “ROAD TO THE EUROPEAN CONVENTION ON HUMAN RIGHTS

Iustinianus Primus Law Review, 2020
The European Convention on Human Rights has been heralded as the most effective system in the world for judicial protection of human rights. This research paper aims to analyze North Macedonia’s constitutional framework for the juridical status ...
Blerton Sinani
doaj  

Dimensiunea dreptului la un proces echitabil (Art. 6 CEDO) [PDF]

Revista Institutului Naţional de Justiţie, 2017
Art. 6 of the European Convention of Human Rights guarantees the right at the equitable and public process of the civil rights and obligations of a person or of any criminal charge or accusation against him.
Sirbu Dan
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Orhuso konvencijos įgyvendinimas: Europos Sąjungos teisė ir Lietuvos administracinė justicija

Teisė, 2009
Straipsnyje nagrinėjami klausimai, susiję su Orhuso konvencijos įgyvendinimu Europos Sąjungoje. Ap­žvelgiami Europos Sąjungos teisės aktų projektai ir naujausi teisės aktai, skirti Orhuso konvencijai įgy­vendinti. Analizuojama Europos Bendrijų Teisingumo
D eimilė Prapiestytė
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source