Results 51 to 60 of about 44,566 (262)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The infringement procedure regarding law on environmental protection of European Union II [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2018
The right of an individual to the environmental protection encompasses material and procedural aspects that correspond to certain obligations of states, in terms of international environmental law.
Bugarski Tatjana D.   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Implementation of standards of the european convention on human rights regarding forced removal of aliens in the European Union law

open access: yesМосковский журнал международного права, 2020
INTRODUCTION. The global migration crisis taking place in the world and especially within the European Union provokes debates regarding the necessity to change the current approaches to the regulation of migration issues.
E. A. Torkunova, K. G. Zharinov
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Forum Acusticum 1996 – The 1st Convention of the European Acoustics Associaction EAA Antwerpen, Belgium 1-4 April 1996

open access: yesArchives of Acoustics, 2014
FORUM ACUSTICUM 1996, the first Convention of the European Acoustics Association EAA-EEIG, is to be held on the campus of the University of Antwerpia, U.I.A. Belgium from 1 to 4 April, 1996. In order to ensure a high quality convention and a large number
Editorial Board Archives of Acoustics
doaj  

HUMAN BEINGS TRAFFICKING IN THE EUROPEAN COURT OF HUMAN RIGHTS CASE-LAW [PDF]

open access: yesChallenges of the Knowledge Society, 2017
After last year’s analysis regarding the European Union’s commitment to fight against the human beings trafficking, we have considered to further explore the human beings trafficking approach in the European Court of Human Rights case-law, the most ...
Laura-Cristiana SPĂTARU-NEGURĂ
doaj  

Prohibition of Reservation to the Principle of Non-Refoulement of Refugees in the Jurisprudence of the European Court of Human Rights [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī
IntroductionAsylum-seeking has emerged as a critical social issue at the international level in recent decades. Every year, millions of refugees leave their home countries or places of residence, seeking refuge in other countries to escape economic ...
Mohammad Reza Mogadasifar   +1 more
doaj   +1 more source

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