Results 151 to 160 of about 1,080,560 (314)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Impact Assessment of European Structural Funds in Andalusia - a CGE Approach [PDF]

open access: yes
In this work we carry out an impact analysis of the European Structural Funds (ESF) to the object of assessing their effect on the GDP, the level of prices or the consumers’ income on the region of Andalusia in the south of Spain. Accordingly, we present
M. Alejandro Cardenete, M. Carmen Lima
core  

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

open access: yesFEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo   +4 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

THE IMPACT OF II PILLAR ON THE MULTIFUNCTIONALITY IN ITALIAN FARMS: ANALYSIS ON THE FARM HOLIDAYS [PDF]

open access: yes
This analysis has examined the relationships between the European funds for rural development and the multifunctionality during a short time, comparing two different situations before and after the Common Agricultural Policy (CAP) reform.
Galluzzo, Nicola
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

The Operational Program Administrative Capacity, Strategic Management Tool

open access: yesEIRP Proceedings, 2017
The strategy of the Operational Program Administrative Capacity addresses the main weaknesses identified in the public administration and it meets the needs and requirements arising both from the relevant EU legislation and from the national incident ...
Manuela Panaitescu
doaj  

The Impact of Structural Funds Policy on European Regions' Growth : A Theoretical and Empirical Approach [PDF]

open access: yes
In this paper, I try to estimate the impact of Structural Funds on the growth rates of Objective 1 European regions during the two first programming periods (1989-2000). I develop a "hybrid" model of economic growth that partially endogenizes the rate of
Mari Carmen Puigcerver-Penalver
core  

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

OPERATIONAL PROGRAMME - DEVELOPMENT OF EASTERN POLAND, 2007 – 2013. DEVELOPMENT OPPORTUNITIES OF LUBLIN VOIVODESHIP AND THE INSTRUMENT OF REGIONAL CONVERGENCE [PDF]

open access: yes
The entire European Union is made up of the elements characterized by, among others, different level of economic development. So far, a measure of the level of the development is Gross Domestic Product per capita.
Magdalena Czerwiñska
core  

Home - About - Disclaimer - Privacy