Results 61 to 70 of about 4,646,129 (305)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
COORDINATES OF THE COHESION POLICY IN ROMANIA DURING THE PROGRAMMING PERIOD 2014 - 2020 [PDF]
Annals of the University of Petrosani: Economics, 2019 Romania is one of the countries that received non-refundable European financial assistance before becoming a Member State of the European Union The experience gained during the 2007-2013 financial programming period in accessing the European Structural ...
DORINA NIȚĂ
doaj
Analysis of the accession of European funds for the environmental policy from 2014 [PDF]
Revista de Studii Financiare, 2021 Economic growth and development have direct impact on environment. In this matter, the concerns about the protection of the environment of the European Union have increased over time.
Răzvan-Aurelian Munteanu
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Romanian Pattern in Absorption and Management of European Structural Funds - A Critical Analysis - [PDF]
The decisions in the cohesion policy have a significant impact upon the offer and supply, in a way that, under the influence of the multipliers, they constantly reconfigure the components of the internal consumption (such as investments, private ...
Monica SUSANU
core +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
THE DEVELOPMENT OF THE ACCESS TO THE LABOR MARKET THROUGH THE IMPROVEMENT OF THE MECHANISMS OF STRUCTURAL FUNDS GRANTING [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2012 As a consequence of the defective management of the European funds, the European Commission has adopted measures to improve the instruments of financial control and to reduce the errors that can lead to incorrect requests of payments from the European ...
EMILIAN M. DOBRESCU +1 more
doaj
The European Development Fund [PDF]
, 1998 The European Development Fund (EDF) was established with the European Community itself. In 1957 the six founding members of the Community decided to create a fund (EDF I) in order to contribute to the economic and social development of a number of African countries that had special links with four member states.1 Some of these African countries were ...
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source