Results 111 to 120 of about 9,278,943 (341)

THE ROMANIAN COMPANY IN THE EUROPEAN SYSTEM [PDF]

open access: yes
Firms, although have the same economic purpose in any geographic or economic space would represent a very different world. Even in the context of integrating each company has its identity is its numerous features, which show in this respect their ...
Ghita Tanase Paul, Virjan Daniela
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Dorin Cimpoeșu, Republica Moldova – criza regimului parlamentar democratic, București. Pro Universitaria, 2015

open access: yesPlural: History, Culture, Society, 2015
Review of the book - Dorin Cimpoeșu, Republica Moldova – criza regimului parlamentar democratic, București.
Sergiu Musteata, Oleg Serebrian
doaj  

ASSESING THE IMPLEMENTATION OF REAL CONVERGENCE IN ROMANIA [PDF]

open access: yes
The convergence is an essential objective of the integration process of Romania in the European Union. Minimizing gaps in the level of development that arise between Romania and the average European Union can not be achieved solely through the use of ...
Ionescu George Horia   +3 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

ASPECTS REGARDING THE COUTRY RISK AND ITS RATING [PDF]

open access: yes
Is Romania affected by the country risk? Country risk, especially the score given by the rating companies is meant to lead to economic growth or recession. Is it possible for only one grade to have that much impact upon the economy?
Cristina Ciumas   +3 more
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

EU Energy Policies Targeting the Environment [PDF]

open access: yesGlobal Economic Observer, 2014
Activities in the energy sector provide the greatest contribution to the emission of greenhouse gases (GHG), which are assigned primary responsibility for producing climate change.
PAUL CALANTER
doaj  

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