Results 61 to 70 of about 7,393,666 (306)

European Integration, Economics, and Voting Behavior in the 2001 British General Election [PDF]

open access: yes, 2009
This paper develops and tests three hypotheses about the effects of European integration on voting behavior in the 2001 British General Election. First, preferences over joining the common currency (Euro) influence voting behavior, as predicted by the ...
Tillman, Erik R.
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Images of Europeans: In-Group Trust and Support for European Integration [PDF]

open access: yes, 2009
Prior research on citizen support for European integration does not consider how individuals’ evaluations of European nationalities are associated with support.
Genna, Gaspare M.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The European Grouping of Territorial Cooperation (EGTC): New Spaces and Contracts for European Integration [PDF]

open access: yes, 2009
The European Union is becoming one undivided continent, where territories are faced with borderless economic, social and environmental challenges while still being governed through traditional institutional boundaries.
Vara-Arribas, Gracia., Spinaci, Gianluca
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Politica și identitatea națională ieri și azi

open access: yesPlural: History, Culture, Society, 2015
The author discusses how the concept of “national identity” has been defined and expressed throughout different ages, peoples and schools of thought.
Oleg Serebrian
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Turkey and the European Union Relations: A Historical Assessment

open access: yesAnkara Avrupa Çalışmaları Dergisi, 2004
Bir yandan "öteki" kavramı bağlamtnda şekillenen karşı lı kl ı korkular, diğeryandan da Atatürk'ün işaret ettiği çağdaş medeniyet seviyesini yakalama hedefiikilemindeki Türkiye, bu makale yay ı nlandığında, son kı rk y ı ldı r dış politikas ı nda ...
Ali Aybey
doaj   +1 more source

Europe Divided? Elites vs. Public Opinion on European Integration. IHS Political Science Series: 2003, No. 88 [PDF]

open access: yes, 2003
This article compares preferences for Europeanizing thirteen policies among European elites, national elites, and public opinion. Elites are more willing to cede national authority in sovereignty areas, but citizens are more favorable to EU social ...
Hooghe, Liesbet
core  

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