Results 71 to 80 of about 9,180,412 (397)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

The Innovativeness of the Economies of European Union Candidate Countries – an Assessment of Their Innovation Gap in Relation to the EU Average

Comparative Economic Research
Innovation is nowadays seen as an essential success factor in achieving economic prosperity and competing in markets. It is one of the most important determinants of the competitive process throughout the world, helping economies catch up with developing
Edyta Dworak
doaj   +1 more source

International Petroleum Fiscal Regimes: Trends in Tax-Royalty Worldwide and in Romania [PDF]

Global Economic Observer, 2014
“Resource nationalism” is a cyclical phenomenon whereby governments assert varying degrees of control over natural resources located within their territories, in an attempt to maximise revenue generation from their national resources.
MARIANA PAPATULICĂ
doaj  

Reference points of European identity: conceptualizing identity beyond the nation-state

Sprawy Narodowościowe. Seria nowa, 2015
Reference points of European identity: conceptualizing  identity beyond the nation-state This article formulates and introduces a comprehensive conceptual framework for understanding the nature and characteristics of collective (state) identities ...
Manfred Kohler
doaj   +1 more source

THE WORK FORCE MIGRATION ABROAD AND ITS ASPECTS IN AN EMERGENT ECONOMY-ROMANIAN MARKET [PDF]

The contemporary migration is considered a phenomenon that proliferates rapidly, its main engine being the globalization. According to the United States Division of Population, the international migration currently includes approximately 200 million ...
Manea Ludmila-Daniela, Muntean Mihaela-Carmen, Nistor Costel   +2 more
core  

Book review: European integration and the communistdilemma: communist responses to Europe in Greece, Cyprusand Italy [PDF]

, 2013
Using an array of interviews with party elites, European Integration and the Communist Dilemma finds that Communist parties in Western Europe have responded to European integration in very different ways, and that they moderate their positions on ...
Keith, Dan
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Dimensionality, ideology and party positions towards European integration

, 2016
The rise of political contestation over European integration has led many scholars to examine the role that broader ideological positions play in structuring party attitudes towards European integration.
Christopher Prosser
semanticscholar   +1 more source

AGAINTS AND FOR THE HIGH SPEED TRAINS' MULTIMPLICATION [PDF]

In this exposure we intend to make visible the situation in which global warming is given by road and air transport, how could be revitalized railways, and how high speed trains could become a preferred mode of transport.
Baciu Adrian, Benea Ciprian
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source