Results 51 to 60 of about 232,375 (311)

A macroeconomic assessment of the European Monetary Union. EUMA Paper Vol. 7, No. 5, April 2010 [PDF]

open access: yes, 2010
Since the inception of Euro in 1999, a single currency and the Economic and Monetary Union (EMU) have past more than ten years. By and large, stepping into EMU represents one of the key aspects of EU’s successful integration.
Wang., Qin
core  

Brexit et espace judiciaire européen

open access: yesEuropean Papers, 2018
(Series Information) European Papers - A Journal on Law and Integration, 2018 3(1), 387-394 | European Forum Insight of 26 April 2018 | (Table of Contents) I. Introduction. - II. Le Royaume-Uni, un État tiers a l'Union Européenne. - III.
Fabienne Jault-Seseke
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Core Curriculum for European Studies in South Eastern Europe. ZEI European Studies and South Eastern Europe Papers, SEE 1, 2002 [PDF]

open access: yes, 2002
[From the Introduction]. The Stability Pact for South Eastern Europe, launched in 1999, aims at transforming the region, which was for so long characterized by ethnic nationalism, war, and animosity, into an integral part of a united Europe.
Mintchev, Emil., Biermann, Rafael
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Theory and Practice of Regional Integration. Jean Monnet/Robert Schuman Paper Series Vol. 8, No. 3 February 2008 [PDF]

open access: yes, 2008
[Introduction]. In this paper I shall briefly outline the classical theories of integration, especially neofunctionalism, which dominated the debate about European integration from the very beginning in the 1950s until the early 1990s.
Laursen, Finn.
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The Promotion of Regional Economic Integration in the EU’s Neighbourhood: CEFTA 2006 and the Agadir Agreement. Bruges Regional Integration & Global Governance Paper 5/2009 [PDF]

open access: yes, 2009
Regional integration scores alluringly high on the hit list of the most promising cures for the world’s major problems. Undoubtedly, the European Union has considerable experience in developing a sophisticated regional integration scheme – but does it ...
Willenberg, Anne
core  

Introduction: European integration as an elite project

open access: yes, 2012
Abstract This chapter defines the volume’s key concepts and introduces the main research questions addressed in the following chapters. Following a review of literature dealing with the challenges of European integration, it focuses on the emergence of various forms of Euroscepticism, Europhobia, and Europhilia among different sectors of
Verzichelli, Luca   +2 more
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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