Results 51 to 60 of about 641,537 (304)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
La gouvernance, ou du Fédéralisme post-national des pouvoirs exécutifs
Phenomenology and Mind, 2015 This text corresponds to a presentation at the «Forum européen des alternatives», held in Paris on May 30-31, 2015. It focuses on the substitution – even at a linguistic level – of a “government” (as a legitimate expression of a democratically ...
Barbara Spinelli
doaj +1 more source
The European Parliament : leadership and 'followership' [PDF]
, 2008 The weakened European Commission and the increasingly assertive European Council and Council of Ministers have contended for control of agenda-setting but it is in the sphere of foreign and security policy that the EU's logic of leaderlessness has been ...
Earnshaw, David, Judge, David
core
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro +10 more
wiley +1 more source
A Tale of Two Serbias? Census-taking in 2002 and 2011
Contemporary Southeastern Europe, 2015 The challenges implicit in census-taking are especially pronounced in the Western Balkans and, very specifically, in Serbia, considering this country’s multi-ethnic and multi-religious makeup, as reflected in territorial delineations, as well as its ...
Mina Djurić Nikolić, Laura Trimajova
doaj
Mid-term review of the Multiannual Financial Framework 2014-2020 – A round-up of key issues at stake
Perspectives on Federalism, 2016 By the end of 2016 the European Commission is expected to present its mid-term review of the Multiannual Financial Framework (MFF) 2014-2020. The results of the review may open the way for a revision of the MFF Regulation.
Sapała Magdalena
doaj +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source