Results 71 to 80 of about 409,783 (282)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Languages, Fees and the International Scope of Patenting [PDF]
This paper analyzes firms’ choices regarding the geographic scope of patent protection within the European patent system. We develop an econometric model at the patent level to quantify the impact of office fees and translation costs on firms’ decision ...
Harhoff, Dietmar +2 more
core
Incidence and Growth of Patent Thickets - The Impact of Technological Opportunities and Complexity [PDF]
, 2011 We investigate incidence and evolution of patent thickets. Our empirical analysis is based on a theoretical model of patenting in complex and discrete technologies.
Graevenitz, Georg von +2 more
core +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Unitary Patent and the Unified Patent Court: Attractive for SMEs?
Croatian Yearbook of European Law and PolicyThe Unitary Patent Package (UPP) was conceived as a means of simplifying and centralising patent protection and enforcement across participating EU Member States. The introduction of a supranational patent jurisdiction and a unitary protection system was
Ivana Božac
doaj +1 more source
Nano is nano is nano or: nanotechnology – a European legal perspective
Nanotechnology Reviews, 2014 In Europe, nanotechnology is perceived as one of the innovative technologies that may drive technological progress. At the same time, Europe historically has followed an approach to cautiously but proactively regulate new technologies, instead of taking ...
Fulda Christian +2 more
doaj +1 more source
The reflection of the struggle of Russian companies for promising markets in the patent statistics
Ekonomika Nauki, 2017 The article analyzes data from the annual report of the European patent agency, reflecting the struggle of industrialized countries for the EU market in the projection of the patent landscape of 2016.
N. G. Kurakova
doaj +1 more source
Cost Benefit Analysis of the Community Patent [PDF]
The creation of a European Community Patent (COMPAT) came a step closer this month when Sweden brokered a preliminary agreement on the issue. In this working paper, Senior Resident Fellow Bruno van Pottelsberghe and Jérôme Danguy use simulations to take ...
Bruno van Pottelsberghe, Jérôme Danguy
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Patenting of technologies related to renewable energy: the case of biodiesel
Revista Tecnologia, 2010 In this work a study of technological tendencies in biodiesel was carried out, based on information extracted of patent documents. The term “patent document” covers published patent applications or granted patents.
Márcia França Fernandes dos Santos +2 more
doaj