Results 41 to 50 of about 15,758,896 (298)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Social Security and Trust Fund Management [PDF]

open access: yes
In this paper we investigate why and to what extent the government should have a social security trust fund, and how it should manage the fund in the face of demographic shocks, based on a simple overlapping-generations model. We show that the government
Oshio, Takashi
core   +2 more sources

Genderová expertka/genderový expert jako opatření ke zkvalitnění projektů ESF? [PDF]

open access: yesGender a Výzkum, 2014
This discussion paper deals with equal opportunities for women and men policy in the Czech Republic financed by the European Social Fund. It presents findings of a case study focused on the position of the “gender expert” which was introduced as ...
Eva Hejzlarová
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

STRUCTURAL AND COHESION FUNDS, A FINANCING ALTERNATIVE FOR ROMANIAN PUBLIC ADMINISTRATION [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2010
In conditions of economic stability and, even more so, in conditions of crisis, when the budgetary resources are subjected to additional stress, public administration has an alternative financing source, by means of accessing the structural and ...
DANA MIHAELA MURGESCU
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The European Social Fund within the Context of the Economic Crisis from Romania

open access: yesTransylvanian Review of Administrative Sciences, 2012
The paper shows the positive traits of the European Social Fund proved by the history of this mechanism which has been applied in the European Community for almost half a century, as well as the measures adopted in order to improve the measures in the ...
Corina CACE   +3 more
doaj   +2 more sources

THE IDEA OF SOCIAL POLICY IN THE EUROPEAN UNION AND ITS IMPACT ON THE MEMBER STATES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2017
This work refers to the mind concept of the social policy, its impact at the European Union level and for each Member State. That way we will have in view of an exhaustive analysis of the European Social Fund and its importance in addressing the social
DANDEŞ ALBERT AUREL
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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